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397583

Radiological Diagnosis Model for Clinically Diagnosed Hypersensitivity Pneumonitis

Article

Last updated: 29 Dec 2024

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Abstract

Introduction: Hypersensitivity Pneumonitis is an immune-mediated interstitial lung disease that manifests in susceptible patients following exposure to an inciting agent(s). It is classified based on symptoms behavior and disease course into three categories acute, subacute and chronic. Diagnosis of Hypersensitivity Pneumonitis is challenging because of the lack of any unique radiological finding distinguishing it from other interstitial lung disease. Hypersensitivity Pneumonitis diagnosis depends on a high level of clinical suspicion, the recognition of antigen exposure, and a constellation of, radiologic, laboratory, and pathologic findings. Creating a diagnostic model including patient age, history of antigen exposure and radiological findings can increase specificity for diagnosis of hypersensitivity pneumonitis. Results: Females represented the vast majority of the included patients accounting for 90% of them. All (100%) of the included patients presented with cough and dyspnea predominantly of grade II (36.7%). Also, all (100%) of included patients reported current status of raising birds. There was a statistically positive and moderate correlation between the patient's dyspnea score and their global CT score with p value 0.005. Conclusion: Radiological diagnostic model with clinical correlation are highly specific diagnostic parameters for hypersensitivity pneumonitis, it offers a high level of inter-observer agreement and internal consistency.

DOI

10.21608/kamj.2024.336320.1016

Keywords

HRCT, CT scoring, Interstitial Lung Disease

Authors

First Name

Sally

Last Name

Tadros

MiddleName

Fouad

Affiliation

Assistant Professor of Radiology, Faculty of Medicine – Cairo University

Email

sallyfouad86@gmail.com

City

-

Orcid

-

First Name

Iman

Last Name

Ibrahim

MiddleName

Mohamed Hamdy

Affiliation

Professor of Radiology, Faculty of Medicine – Cairo University

Email

imhamdy@gmail.com

City

-

Orcid

-

First Name

Yara

Last Name

Ahmed

MiddleName

Alaa

Affiliation

Radiology Department, Shobra General Hospital, Cairo, Egypt

Email

yayaalaa44@gmail.com

City

-

Orcid

-

First Name

Reem

Last Name

El-Korashy

MiddleName

Ibrahim

Affiliation

Professor of Pulmonology, Faculty of Medicine – Cairo University

Email

reem.elkorashy@kasralainy.edu.eg

City

-

Orcid

-

First Name

Rania

Last Name

Zeitoun

MiddleName

Aly

Affiliation

Assistant Professor of Radiology, Faculty of Medicine – Cairo University

Email

raniazeitoun@gmail.com

City

-

Orcid

0000-0002-4425-768X

Volume

29

Article Issue

1

Related Issue

49363

Issue Date

2023-06-01

Receive Date

2024-11-13

Publish Date

2023-06-01

Page Start

21

Page End

28

Print ISSN

1687-4625

Online ISSN

2356-8097

Link

https://kamj.journals.ekb.eg/article_397583.html

Detail API

https://kamj.journals.ekb.eg/service?article_code=397583

Order

397,583

Type

Original Article

Type Code

2,515

Publication Type

Journal

Publication Title

Kasr Al Ainy Medical Journal

Publication Link

https://kamj.journals.ekb.eg/

MainTitle

Radiological Diagnosis Model for Clinically Diagnosed Hypersensitivity Pneumonitis

Details

Type

Article

Created At

29 Dec 2024