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359615

The broad-spectrum antiparasitic ivermectin against COVID-19

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Last updated: 05 Jan 2025

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Abstract

Ivermectin, the FDA-approved broad-spectrum antiparasitic drug, has recently shown excellent antiviral effects against many viral infections. This effect was especially important in the current pandemic infection of COVID-19. There are reports that ivermectin inhibited the replication of the virus in 48 h. Studies have been done on other viral infections and on this virus and . The results showed that it affects the viral replication by its effect on the protein transfer between the cytoplasm and nucleus inside the host cells. More information is still needed to approve its use in the treatment and prevention of COVID-19 pandemic, which will necessitate more studies to adjust the dose and mode of administration.

DOI

10.4103/kamj.kamj_37_20

Keywords

COVID-19, SARS-CoV-2, importin, Ivermectin, RNA viruses, viral inhibition, viral replication

Authors

First Name

Nadia A.

Last Name

El Dib

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Orcid

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First Name

Mona I.

Last Name

Ali

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Orcid

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Volume

26

Article Issue

2

Related Issue

48363

Issue Date

2020-12-01

Receive Date

2020-09-01

Publish Date

2020-12-30

Print ISSN

1687-4625

Online ISSN

2356-8097

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https://kamj.journals.ekb.eg/article_359615.html

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https://kamj.journals.ekb.eg/service?article_code=359615

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359,615

Publication Type

Journal

Publication Title

Kasr Al Ainy Medical Journal

Publication Link

https://kamj.journals.ekb.eg/

MainTitle

The broad-spectrum antiparasitic ivermectin against COVID-19

Details

Type

Article

Created At

29 Dec 2024