Viral Hemorrhagic Fever Diseases are critical health problems worldwide. Several outbreaks of hemorrhagic fever diseases have emerged in the last few years in different countries, particularly in tropical and subtropical regions of Africa, raising concerns in our country, Egypt. The Ministry of Health and Population in Egypt has issued orders and guidelines for the prevention and treatment of Marburg virus infections, as well as for dealing with confirmed and suspected cases of dengue fever. Egypt is on high alert to prevent the entry of Marburg virus infections into the country and to manage and control dengue virus infections. The environmental conditions and non-primate reservoirs of these viruses in areas, including Egypt, can transmit infections to humans, leading to Hemorrhagic fever diseases. The ease of travel and transportation between countries, coupled with a low level of prevention and infection control measures, makes the spread of these infections possible in various locations. In this article, we present selected causative agents of hemorrhagic fever diseases, such as the Ebola virus, Marburg virus, and Dengue fever viruses. We also discuss the properties of these viruses, mode of transmission, clinical and laboratory diagnosis, treatment, infection control, and prevention of these diseases.