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296500

Boldo phytochemical and pharmacological activities updated Mini-review

Article

Last updated: 29 Dec 2024

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Section A: Natural Products and Metabolomics

Abstract

Peumus boldus is a plant belonging to the family Monimiaceae. It is native small perennial tree, dispersed globally, commonly known as boldo. It is distributed mainly in South America (Chile), and the Mediterranean region. It has a several uses in traditional medicine Boldo leaves and bark are the main parts of the plant known with it richness with mainly alkaloids. They are responsible for its pharmacological activities. Boldine is the most abundant detected alkaloid within boldo. Other non-alkaloids identified compounds as phenolic compounds, flavon-3-ol (mainly isorhamnetin and kaempferol) and glycosides. Moreover essential oils, mainly 1,8-cineole, p-cymene, Limonene, and ascaridole. These chemical compositions may be responsible for in vivo and in vitro biological activities as antioxidant activity, antimicrobial activity, antifungal activity, anti-parasitic activity, and insecticidal effect. The main aim of this review is to present an updated overview of the significance of pharmacological activities and chemical composition of the boldo and its isolated alkaloid boldine.

DOI

10.21608/erurj.2023.203801.1018

Keywords

Alkaloids, Phenolics, Anticancer activity, antimicrobial activity

Authors

First Name

Mostafa

Last Name

Abouelela

MiddleName

B.

Affiliation

Department of Pharmacognosy, Faculty of Pharmacy, Egyptian Russian University, Badr City, Cairo-Suez Road, Cairo 11829, Egypt.

Email

dr_m.besheer@hotmail.com

City

CAIRO

Orcid

-

First Name

Reem

Last Name

Naimy

MiddleName

A.

Affiliation

Pharm D Program, Faculty of Pharmacy, Egyptian Russian University, Badr City, Cairo-Suez Road, Cairo11829, Egypt.

Email

202429@eru.edu.eg

City

-

Orcid

-

First Name

Omnya

Last Name

Elshafey

MiddleName

A.

Affiliation

Pharm D Program, Faculty of Pharmacy, Egyptian Russian University, Badr City, Cairo-Suez Road, Cairo11829, Egypt.

Email

202420@eru.edu.eg

City

-

Orcid

-

First Name

Momen

Last Name

Mahmoud

MiddleName

M.

Affiliation

Pharm D Program, Faculty of Pharmacy, Egyptian Russian University, Badr City, Cairo-Suez Road, Cairo11829, Egypt.

Email

192100@eru.edu.eg

City

-

Orcid

-

First Name

Mahmoud

Last Name

Elgez

MiddleName

M.

Affiliation

Pharm D Program, Faculty of Pharmacy, Egyptian Russian University, Badr City, Cairo-Suez Road, Cairo11829, Egypt.

Email

192330@eru.edu.eg

City

-

Orcid

-

First Name

Mariem

Last Name

Ahmed

MiddleName

M.

Affiliation

Pharm D Program, Faculty of Pharmacy, Egyptian Russian University, Badr City, Cairo-Suez Road, Cairo11829, Egypt.

Email

202419@eru.edu.eg

City

-

Orcid

-

First Name

Nada

Last Name

Abdallah

MiddleName

M.

Affiliation

Pharm D Program, Faculty of Pharmacy, Egyptian Russian University, Badr City, Cairo-Suez Road, Cairo11829, Egypt.

Email

202407@eru.edu.eg

City

-

Orcid

-

First Name

Yousab

Last Name

Boshra

MiddleName

A.

Affiliation

Pharm D Program, Faculty of Pharmacy, Egyptian Russian University, Badr City, Cairo-Suez Road, Cairo11829, Egypt.

Email

192057@eru.edu.eg

City

-

Orcid

-

First Name

Ahmed

Last Name

Mohamed

MiddleName

S.

Affiliation

Pharm D Program, Faculty of Pharmacy, Egyptian Russian University, Badr City, Cairo-Suez Road, Cairo11829, Egypt.

Email

192322@eru.edu.eg

City

-

Orcid

-

First Name

Asmaa

Last Name

Saad

MiddleName

E.

Affiliation

Pharm D Program, Faculty of Pharmacy, Egyptian Russian University, Badr City, Cairo-Suez Road, Cairo11829, Egypt.

Email

202431@eru.edu.eg

City

-

Orcid

-

First Name

Maha

Last Name

Abdelhay

MiddleName

I.

Affiliation

Pharm D Program, Faculty of Pharmacy, Egyptian Russian University, Badr City, Cairo-Suez Road, Cairo11829, Egypt.

Email

202401@eru.edu.eg

City

-

Orcid

-

First Name

Ahmed

Last Name

Ali

MiddleName

M.

Affiliation

Pharm D Program, Faculty of Pharmacy, Egyptian Russian University, Badr City, Cairo-Suez Road, Cairo11829, Egypt.

Email

202024@eru.edu.eg

City

-

Orcid

-

First Name

Ehab

Last Name

Sayed

MiddleName

El

Affiliation

Pharm D Program, Faculty of Pharmacy, Egyptian Russian University, Badr City, Cairo-Suez Road, Cairo11829, Egypt.

Email

192082@eru.edu.eg

City

-

Orcid

-

First Name

Osama

Last Name

Mohamed

MiddleName

E.

Affiliation

Pharm D Program, Faculty of Pharmacy, Egyptian Russian University, Badr City, Cairo-Suez Road, Cairo11829, Egypt.

Email

192025@eru.edu.eg

City

-

Orcid

-

First Name

Sara

Last Name

Mohamed

MiddleName

E.

Affiliation

Pharm D Program, Faculty of Pharmacy, Egyptian Russian University, Badr City, Cairo-Suez Road, Cairo11829, Egypt.

Email

202430@eru.edu.eg

City

-

Orcid

-

First Name

Ahmed

Last Name

Mohamed

MiddleName

-

Affiliation

Pharm D Program, Faculty of Pharmacy, Egyptian Russian University, Badr City, Cairo-Suez Road, Cairo11829, Egypt.

Email

192051@eru.edu.eg

City

-

Orcid

-

First Name

Omayma

Last Name

ElGindi

MiddleName

-

Affiliation

Department of Pharmacognosy, Faculty of Pharmacy, Egyptian Russian University, Badr City, Cairo-Suez Road, Cairo 11829, Egypt.

Email

omayma-elgindi@eru.edu.eg

City

-

Orcid

-

Volume

2

Article Issue

2

Related Issue

41033

Issue Date

2023-04-01

Receive Date

2023-04-03

Publish Date

2023-04-01

Page Start

308

Page End

319

Print ISSN

2812-6211

Online ISSN

2812-622X

Article File

ERURJ_Volume 2_Issue 2_Pages 308-319.pdf

PDF . 271.6kB

Link

https://erurj.journals.ekb.eg/article_296500.html

Detail API

https://erurj.journals.ekb.eg/service?article_code=296500

Order

296,500

Type

Mini-review

Type Code

2,450

Publication Type

Journal

Publication Title

ERU Research Journal

Publication Link

https://erurj.journals.ekb.eg/

MainTitle

Boldo phytochemical and pharmacological activities updated Mini-review

Details

Type

Article

Created At

29 Dec 2024