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283010

Pomegranates bioactive metabolites and biological activities: an updated review

Article

Last updated: 29 Dec 2024

Subjects

-

Tags

Section A: Natural Products and Metabolomics

Abstract

Pomegranate (Punica granatum L.) is a fruit that is widely consumed as fresh fruit and juice. The use of pomegranate fruit dates from ancient times and literature about its therapeutic qualities has echoed throughout the ages. Several in vitro and in vivo studies have shown how this fruit acts as antioxidant, antidiabetic, and hypolipidemic and shows antibacterial, antiparasitic antifungal, anti-inflammatory, antiviral, and anti-carcinogenic activities. The fruit also potentiates cardiovascular and oral health. These beneficial physiological effects may also have preventive applications in a variety of diseases such as (renal and hepatic toxicity). The health benefits of pomegranate have been attributed to its wide range of chemicals and extracts, which are predominantly polyphenols, including primarily hydrolysable ellagitannins, anthocyanins, sugars, organic acids and other polyphenols. The aim of this review is to present an updated overview of the functional, medical, chemical and physiological properties of this fruit and / or its agri-food residues.

DOI

10.21608/erurj.2023.283010

Keywords

pomegranate, Polyphenols, ellagitannin, anthocyanins, agri-food residue

Authors

First Name

Mahmoud

Last Name

Abdelkarim

MiddleName

Osama

Affiliation

Pharm D Program, Faculty of Pharmacy, Egyptian Russian University, Badr City, Cairo-Suez Road, Cairo 11829, Egypt

Email

192098@eru.edu.eg

City

-

Orcid

-

First Name

Abdallah

Last Name

Ebrahim

MiddleName

Mahmoud

Affiliation

Pharm D Program, Faculty of Pharmacy, Egyptian Russian University, Badr City, Cairo-Suez Road, Cairo 11829, Egypt

Email

192070@eru.edu.eg

City

-

Orcid

-

First Name

Moamen

Last Name

Eissa

MiddleName

Morad Fathy

Affiliation

Pharm D Program, Faculty of Pharmacy, Egyptian Russian University, Badr City, Cairo-Suez Road, Cairo 11829, Egypt

Email

192003@eru.edu.eg

City

-

Orcid

-

First Name

Moaz

Last Name

Ali

MiddleName

Essam

Affiliation

Pharm D Program, Faculty of Pharmacy, Egyptian Russian University, Badr City, Cairo-Suez Road, Cairo 11829, Egypt

Email

192064@eru.edu.eg

City

-

Orcid

-

First Name

Ahmed

Last Name

Shaban

MiddleName

Lamaey

Affiliation

Pharm D Program, Faculty of Pharmacy, Egyptian Russian University, Badr City, Cairo-Suez Road, Cairo 11829, Egypt

Email

192056@eru.edu.eg

City

-

Orcid

-

First Name

Abdelaty

Last Name

Ahmed

MiddleName

Mohamed

Affiliation

Pharm D Program, Faculty of Pharmacy, Egyptian Russian University, Badr City, Cairo-Suez Road, Cairo 11829, Egypt

Email

192024@eru.edu.eg

City

-

Orcid

-

First Name

Mohamed

Last Name

Hassan

MiddleName

Mahmoud

Affiliation

Pharm D Program, Faculty of Pharmacy, Egyptian Russian University, Badr City, Cairo-Suez Road, Cairo 11829, Egypt

Email

192095@eru.edu.eg

City

-

Orcid

-

First Name

Ahmed

Last Name

Ahmed

MiddleName

Abdelfattah

Affiliation

Pharm D Program, Faculty of Pharmacy, Egyptian Russian University, Badr City, Cairo-Suez Road, Cairo 11829, Egypt

Email

192110@eru.edu.eg

City

-

Orcid

-

First Name

Karim

Last Name

Eltayeb

MiddleName

Kamal

Affiliation

Pharm D Program, Faculty of Pharmacy, Egyptian Russian University, Badr City, Cairo-Suez Road, Cairo 11829, Egypt

Email

192096@eru.edu.eg

City

-

Orcid

-

First Name

Omar

Last Name

Ahmed

MiddleName

Ali

Affiliation

Pharm D Program, Faculty of Pharmacy, Egyptian Russian University, Badr City, Cairo-Suez Road, Cairo 11829, Egypt

Email

192007@eru.edu.eg

City

-

Orcid

-

First Name

Ali

Last Name

Mohamed

MiddleName

Ahsraf

Affiliation

Pharm D Program, Faculty of Pharmacy, Egyptian Russian University, Badr City, Cairo-Suez Road, Cairo 11829, Egypt

Email

192076@eru.edu.eg

City

-

Orcid

-

First Name

Mohamed

Last Name

Abdelsalam

MiddleName

Wael

Affiliation

Pharm D Program, Faculty of Pharmacy, Egyptian Russian University, Badr City, Cairo-Suez Road, Cairo 11829, Egypt

Email

192054@eru.edu.eg

City

-

Orcid

-

First Name

Alaa

Last Name

Elsheikh

MiddleName

Gamal

Affiliation

Pharm D Program, Faculty of Pharmacy, Egyptian Russian University, Badr City, Cairo-Suez Road, Cairo 11829, Egypt

Email

192062@eru.edu.eg

City

-

Orcid

-

First Name

Khaled

Last Name

Mostafa

MiddleName

Mohamed

Affiliation

Pharm D Program, Faculty of Pharmacy, Egyptian Russian University, Badr City, Cairo-Suez Road, Cairo 11829, Egypt

Email

192078@eru.edu.eg

City

-

Orcid

-

First Name

Said

Last Name

Said

MiddleName

Basuony

Affiliation

Pharm D Program, Faculty of Pharmacy, Egyptian Russian University, Badr City, Cairo-Suez Road, Cairo 11829, Egypt

Email

1920272@eru.edu.eg

City

-

Orcid

-

First Name

Sara

Last Name

Mohamed

MiddleName

Ismail

Affiliation

Pharm D Program, Faculty of Pharmacy, Egyptian Russian University, Badr City, Cairo-Suez Road, Cairo 11829, Egypt

Email

192066@eru.edu.eg

City

-

Orcid

-

First Name

Aya

Last Name

Ali

MiddleName

Hussein

Affiliation

Pharm D Program, Faculty of Pharmacy, Egyptian Russian University, Badr City, Cairo-Suez Road, Cairo 11829, Egypt

Email

192079@eru.edu.eg

City

-

Orcid

-

First Name

Shrouk

Last Name

Mohamed

MiddleName

Ahmed

Affiliation

Pharm D Program, Faculty of Pharmacy, Egyptian Russian University, Badr City, Cairo-Suez Road, Cairo 11829, Egypt

Email

192040@eru.edu.eg

City

-

Orcid

-

First Name

Ahmed

Last Name

Mahmoud

MiddleName

Nasr Eldin

Affiliation

Pharm D Program, Faculty of Pharmacy, Egyptian Russian University, Badr City, Cairo-Suez Road, Cairo 11829, Egypt

Email

192030@eru.edu.eg

City

-

Orcid

-

First Name

Abdelrahman

Last Name

Moaaz

MiddleName

Faik

Affiliation

Pharm D Program, Faculty of Pharmacy, Egyptian Russian University, Badr City, Cairo-Suez Road, Cairo 11829, Egypt

Email

192097@eru.edu.eg

City

-

Orcid

-

First Name

Reham

Last Name

Mekky

MiddleName

Hassan

Affiliation

Pharmacognosy Department, Faculty of Pharmacy, Egyptian Russian University, Badr City, Cairo-Suez Road, Cairo 11829, Egypt

Email

reham-mekky@eru.edu.eg

City

Badr City Cairo

Orcid

0000-0001-5613-5666

First Name

Omayma

Last Name

Elgindi

MiddleName

-

Affiliation

Pharmacognosy Department, Faculty of Pharmacy, Egyptian Russian University, Badr City, Cairo-Suez Road, Cairo 11829, Egypt

Email

omayma-elgindi@eru.edu.eg

City

-

Orcid

-

Volume

2

Article Issue

1

Related Issue

39368

Issue Date

2023-01-01

Receive Date

2023-01-24

Publish Date

2023-01-01

Page Start

121

Page End

160

Print ISSN

2812-6211

Online ISSN

2812-622X

Link

https://erurj.journals.ekb.eg/article_283010.html

Detail API

https://erurj.journals.ekb.eg/service?article_code=283010

Order

4

Type

Review article

Type Code

2,449

Publication Type

Journal

Publication Title

ERU Research Journal

Publication Link

https://erurj.journals.ekb.eg/

MainTitle

Pomegranates bioactive metabolites and biological activities: an updated review

Details

Type

Article

Created At

29 Dec 2024