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320255

Eco-friendly and Regiospecific synthesis of Novel (5-oxo-4,4-diphenylimidazolidin-2-ylidene)cyanamide Derivatives

Article

Last updated: 05 Jan 2025

OverviewSimilar Items

Subjects

-

Tags

Chemistry

Abstract

The Ultrasonic (US) technique is used in the present work as an eco-friendly method for the synthesis of (5-oxo-4,4-diphenylimidazolidin-2-ylidene)cyanamide derivatives. A simple and efficient method has been described for the alkylation of (5-oxo-4,4-diphenylimidazolidin-2-ylidene)cyanamide (1). Besides the IR and NMR spectra, the regioselectivity of the N-alkylation is chemically achieved. Furthermore, fusion of sodium salt of 1 with ethyl bromide in DMF as solvent using ultrasound irradiation as a source of power afforded (1,3-diethyl-5-oxo-4,4-diphenylimidazolidin-2-ylidene)cyanamide (9).

DOI

10.21608/sjsci.2023.232963.1120

Keywords

ultrasonic technique, Eco-friendly, Cyanoguanidinophenytoin, Regioselectivity, alkylation

Authors

First Name

Amer

Last Name

Amer

MiddleName

A.

Affiliation

Department of Chemistry, Faculty of Science, Sohag University, Sohag 82524, Egypt.

Email

amer_chem@yahoo.com

City

Sohag

Orcid

org/0000-0001-7112-9918

First Name

Doaa

Last Name

Ahmed

MiddleName

H.

Affiliation

Department of Chemistry, Faculty of Science, Sohag University, Sohag 82524, Egypt.

Email

sunriseh51@yahoo.com

City

-

Orcid

-

First Name

Amr

Last Name

Moustafa

MiddleName

H.

Affiliation

Department of Chemistry, Faculty of Science, Sohag University, Sohag 82524, Egypt., Faculty of Science, King Salman International University, Ras Sudr, Sinai 46612, Egypt.

Email

amr_hassanegypt@ymail.com

City

-

Orcid

-

Volume

9

Article Issue

1

Related Issue

42891

Issue Date

2024-03-01

Receive Date

2023-08-30

Publish Date

2024-01-01

Page Start

64

Page End

68

Print ISSN

2357-0938

Online ISSN

2974-4296

Article File

SJSCI_Volume 9_Issue 1_Pages 64-68.pdf

PDF . 334.5kB

Link

https://sjsci.journals.ekb.eg/article_320255.html

Detail API

https://sjsci.journals.ekb.eg/service?article_code=320255

Order

320,255

Type

Regular Articles

Type Code

2,359

Publication Type

Journal

Publication Title

Sohag Journal of Sciences

Publication Link

https://sjsci.journals.ekb.eg/

MainTitle

Eco-friendly and Regiospecific synthesis of Novel (5-oxo-4,4-diphenylimidazolidin-2-ylidene)cyanamide Derivatives

Details

Type

Article

Created At

29 Dec 2024