Background: Resilience affect the coping with adversities that its faced by hemodialysis patients. Accordingly, diverse methods of non-pharmacological interventions, such as (mandala coloring) that foster self-expression and bear down emotional conflict is so important to increase resilience and flow among hemodialysis patients. Study aim: this study aimed to assess levels of resilience among hemodialysis patients. Design: A quasi-experimental design was used in this study. Setting: The present study was conducted at Hemodialysis Unit affiliated to Suez Canal University Hospital and the international 30 July center, Ismailia city. Sample: A sample of 64 Hemodialysis patients with chronic hemodialysis and without antianxiety or antidepressant medications Tools: Three tools were used in this study. First tool: Demographic characteristics and Clinical characteristics, Second tool: structured interviewing questionnaire and the third tool: The Connor-Davidson Resilience scale (CD-RISC). Results: the results in this study revealed that: 100% had a mild level of resilience before the intervention. Regarding post and follow-up phases, resilience levels increased among the intervention group compared with the control group. Conclusion: the study concluded that; the mandala coloring nurse-led intervention program significantly improved psychological resilience among hemodialysis patients in the post-follow-up study phases compared with the pre-program phase. Recommendation: Research into the impact of mandala coloring and chronically ill patients' resilience and quality of life will be useful for future research reference.

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Key words: Hemodialysis patients, Mandala coloring, Resilience.