Music is a global language in the world and one of the most important indicators of the degree of civilization and development of a nation. This study aimed to shed light on musicians in ancient times. Through a comparative study of those talented people concerning their status, instruments, groups, clothes and their. titles as well. This paper is divided into three parts, musicians in ancient Egypt, musicians in Greco Roman Egypt and musicians in Byzantine Egypt. The findings of this study high lightened the differences and similarities between those periods concerning musicians which was obvious at many points such as the relationship between religion and music, musical competitions specially at the Greco-Roman period, the different regards to musicians according to the instrument they played or to the musical group they belonged to, musical educational classes, and the fashionable clothes they wore. The most important result of this study is to prove that the origin of Symphonia is ancient Egyptian not Greek.