Background and Aim: This study was aimed to compare the implant stability of Hyaluronic Acid coated implants with Sandblasted Large Thread Acid Etched surface implants placed in the maxillary posterior area. Methods: 30 Adults patients with at least one missing maxillary posterior tooth were randomly assigned into two equal parallel groups with a 1:1 allocation ratio to receive either HA coated Titanium Implant (test group) or SAE Implants (control group). Outcomes measured: The primary outcome was implant stability as measured by the Resonance Frequency Analysis (RFA) via the Osstell ISQ system ® at baseline (T0) and 6 (T1) and 12 (T2) weeks post-operatively. The secondary outcome measured involved surgical wound healing based on Landry index evaluated at 7th and 14th day post-operatively. Results: Regarding implant stability, results of the primary implant stability at (T0) revealed no statistically significant differences between the two study groups (P= 0.129). Contrarily, the secondary implant stability at (T1) and (T2) weeks showed statistically significant greater ISQ values in the HA coated implant group than SAE implants group (P≤0.001 at T1and T2). On the 14th postoperative day, the surgical wound healing in the HA coated Implant group was either very good or excellent, while in SAE implants group varied from good to excellent soft tissue healing. The differences in soft tissue index were statistically significant between the two groups (P=0.005). Conclusion: HA-coated implants with hydrophilic surfaces achieve faster osseointegration than those without modification within a shorter period, making them suitable candidates for early loading protocols.