Aim
Is to clinically evaluate the efficacy of intra-articular (PRP) injections in
combination with arthrocentesis compared to (i-PRF) injections in combination
with arthrocentesis in management of patients with (TMJ OA).
Materials & methods:
45 eligible patients with (TMJ-OA) were selected from the outpatient clinic of
Oral and Maxillofacial Surgery Department, October University for modern
sciences and arts, Cairo, Egypt.
Patients were randomly assigned one of the three groups: Group I: patients
treated with arthrocentesis (control group) Group II: patients treated with
arthrocentesis and intra-articular (PRP) injection Group III: patients treated
with arthrocentesis and intra-articular (i-PRF) injection
The three groups were compared to each other regarding maximum mouth
opening (MMO) & pain improvement using visual analogue scale (VAS)
Results:
Comparing the three groups, the VAS scores variation between them was
statistically non-significant (p > 0.05) preoperatively, while at 1 month, 3 month
and 6 month postoperatively there was significant decrease (P ≤ 0.05) at VAS
scores with best results for group III followed by group II in comparison with
group I.
Comparing the MMO results between the three groups showed statistically
non-significant (p > 0.05) preoperatively, while at 1 month, 3 month and 6
month postoperatively there was a significant increase (P ≤ 0.05) at the MMO
scores with best results for group III followed by group II in comparison with
group I.

Conclusion
Intraarticular injection of i-PRF following arthrocentesis is a successful
treatment with better comparable reported results than intraarticular injection of
PRP following arthrocentesis in management of TMJ OA.