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363870

THE IMMUNOMODULATORY AND HISTOLOGICAL EFFECTS OF Nigella sativa SEEDS ON BROILER CHICKENS

Article

Last updated: 29 Dec 2024

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Subjects

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Tags

Animal and Poultry Sciences

Abstract

This study investigates the effects of dietary supplementation with Nigella sativa seeds (NSS) on immune parameters and the histological microscopic structure of lymphoid organs in Arbor Acres broiler chicks. A total of 140 unsexed one-day-old chicks were randomly assigned to four groups with seven replicates each. The control group received a basal diet without supplements, while the other groups were fed the basal diet supplemented with NSS at concentrations of 0.5%, 1.0%, and 1.5%. The group supplemented with 0.5% NSS showed significantly higher white blood cell counts compared to other groups. The heterophil/ lymphocyte ratio was significantly elevated in the 0.5% NSS group. Plasma α-globulin concentration increased significantly in the 1.0% NSS group compared to the 0.5% group. Phagocytic activity was enhanced in all NSS-supplemented groups compared to the control. Bactericidal activity improved notably in the control, 1.0%, and 1.5% NSS groups. The lymphocyte transformation test concentration was significantly higher in the 1.0% NSS group. Haemagglutination inhibition against Newcastle disease virus was highest in the 1.0% NSS group. The weight of the bursa of Fabricius was significantly greater in the 1.0% and 1.5% NSS groups. Histologically, chicks fed with 0.5%, 1.0%, and 1.5% NSS had significantly longer villi, and the 0.5% NSS group exhibited larger bursal follicular areas. In conclusion, incorporating 1.0% NSS into broiler diets positively influenced immune responses, lymphoid organs, hematological parameters, and improved organ health histologically.

DOI

10.21608/jaesj.2024.210673.1092

Keywords

broiler, Immune, Histological, lymphoid, Nigella Sativa

Authors

First Name

Mohamed

Last Name

Hassan

MiddleName

I.

Affiliation

Livestock Research Department, Arid Lands Cultivation Research Institute, City of Scientific Research and Technological Applications (SRTA- City), New Borg El-Arab, Alexandria, Egypt.

Email

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City

-

Orcid

-

First Name

Saber

Last Name

Hassan

MiddleName

Shihata

Affiliation

Animal and Poultry Production Department, Faculty of Agriculture, Damanhour University, Egypt

Email

saber.shihata77@gmail.com

City

-

Orcid

-

Volume

22

Article Issue

3

Related Issue

44558

Issue Date

2023-12-01

Receive Date

2023-05-13

Publish Date

2023-12-01

Page Start

317

Page End

340

Print ISSN

1687-1464

Online ISSN

2735-5098

Article File

JAESJ_Volume 22_Issue 3_Pages 317-340.pdf

PDF . 588.7kB

Link

https://jaesj.journals.ekb.eg/article_363870.html

Detail API

https://jaesj.journals.ekb.eg/service?article_code=363870

Order

363,870

Type

Full research articles

Type Code

2,324

Publication Type

Journal

Publication Title

Journal of Agricultural and Environmental Sciences

Publication Link

https://jaesj.journals.ekb.eg/

MainTitle

THE IMMUNOMODULATORY AND HISTOLOGICAL EFFECTS OF Nigella sativa SEEDS ON BROILER CHICKENS

Details

Type

Article

Created At

29 Dec 2024