Roselle plays a pivotal role in the pharmaceutical and food sectors due to its economic and cultural significance. In response to the challenges posed by climate change, identifying the optimal sowing date for Roselle crop in light with climate change has become crucial in agricultural practices. This study aimed to explore the influence of sowing dates on the nutrients, biochemical content, and quality of Roselle in the newly reclaimed soil of Aswan governorate. Four sowing dates were implemented in this experiment including April 15^th, April 30^th, May 15^th and May 30^th. The diverse sowing dates resulted in significant differences in photosynthetic pigments and biochemical components such as total phenols, total flavonoids, antioxidant activity, and vitamin C, along with variations in nutrient content (N, P, K, Ca, Fe, and Zn). Notably, sowing on May 15^th consistently yielded the highest values for these traits across both seasons. The results underscore that planting on May 15^th enhanced the nutritional and biochemical profile of Roselle, contributing to elevated levels of economic and health-related attributes. Specifically, this sowing date significantly improved the biochemical contents and overall quality of Roselle. Consequently, based on the findings of this study, it is recommended to sow Roselle in the middle of May to augment the pharmaceutical properties and quality.