The present study was carried out during the three successive seasons i.e., 2019/2020, 2020/2021 and 2021/2022 at Fac. Agric. Farm, Assiut University, Egypt. The objective of this study was to estimate observed and expected responses to selection for grain yield and its components in two cycles of pedigree line selection  and one cycle of late selection in one segregating population of bread wheat (Triticum aestivum. L). The results showed that the observed direct responses of pedigree line selection for grain yield/plant (selection criterion) were 11.94, 27.50 and 28.67% after one, 30.82, 22.21 and 29.07% after two cycles of early pedigree line selection and 40.96, 31.68 and 39.08% after one cycle of late selection as accounted relative to unselected bulk sample, better parent and mid parents, respectively. The final direct responses for grain yield/plant after two early cycles and one late cycle were larger than cycle one of pedigree line selection, except for better parent and mid parents in early selections.