Background: laparoscopic transperitoneal uriterolithotomy is a minimally invasive surgical procedure used to remove stones from the ureter. Purpose: To assess the safety, feasibility, and efficacy of laparoscopic transperitoneal ureterolithotomy (LTPU) in the treatment of recurrent distal ureteric stones in patients with previous open retroperitoneal uretrolithotomy - in whom another transperitoneal surgery was performed. Methodology: A prospective study was conducted at the department of Urology, Sohag University hospital. All patients with recurrent distal ureteric stones who attended our institute between January 2019 and March 2023 and scheduled for LTPU were consecutively included. Patients were followed postoperatively for subjective improvements. The statistical analysis was carried with SPSS software version 18 for windows. Results: A total of 44 patients (30 men and 14 women) were included in the study). No conversion to open surgery was needed in any of the patients. The mean operative time was significantly longer in these 11 patients who underwent LTPU on the same side of the previously mentioned transperitoneal surgeries than in patients with stones on contralateral side (149 ±11 min vs. 88 ±7 min, p < 0.05). No major complications occurred either intraoperative or postoperative. During the follow-up, one patient developed small distal ureteral stone (7 mm) which was managed successfully. Conclusions: Previous transperitoneal laparoscopic surgery in patients with previous open retroperitoneal ureterolithotomy seems to have no significant impact on transperitoneal ureterolithotomy for recurrent ureteric stones in these patients.