Reducing dependency on fossil fuels and the corresponding emissions, absorption chiller systems offer a sustainable and eco-friendly alternative to conventional refrigeration systems. To determine the success of a solar thermal air conditioning system, climate data was collected for Cairo, Egypt, between May and September 2023. Many factors affecting the performance of the system were studied, including the area of solar collector, inclination angle, temperature of hot and chilled water, and mass flow rate. The results of the simulation demonstrate that at a high system Coefficient of Performance (COP), the solar absorption chiller can consistently generate cooling. The system's cooling load requirement is 26.4 kW, and its maximum COP is 0.52. A system consisting of an 80 °C hot water inlet, a 3780-liter solar water storage tank, a 15-degree solar collector slope, and a 1.19 kg/s hot water flow rate was able to achieve peak performance. The solar-powered cooling system was investigated using a simulation tool known as TRNSYS (Transient System Simulation Software). The compound PSC area increases from 20 to 50 m2, resulting in a decrease in the amount of energy required from the auxiliary heater from 23 to 21.5 kW. The outcomes also demonstrated that the COP rose until it reached 0.52, when hot and chilled water temperatures rose. When analyzing the energy during a typical summer, it was found that the solar collector can store an average of 15.3 kW of energy. During these periods, the auxiliary heater consumed an average of 20.5 kW of electricity.