ABSTRACT

Background: Premature rupture of membranes (PROM) constitutes one of the major dilemmas in current obstetric practice.

Patients and methods: A Prospective laboratory-based study was carried out on 101 patients at department of Obstetrics and Gynecology at Minia Maternity and Children university hospital, Egypt from January 2023 to December 2023.

Aim of the study: detection of local dominant microorganism strains isolated from women with Preterm Premature Rupture of Membrane attending Minia Maternity University Hospital.

Results: Th isolated strains were: 29(28.7%) patients had E. coli, 9(8.9%) patients had coagulase negative staphylococcus, 23(22.8%) patients had Staphylococcus aureus, 26(25.7%) patients had Klebsiella pneumonia, 16(15.8%) patients had Acinetobacter baumannii,1(0.99%) patient had Enterococcus spp, 7(6.9%) patients had non-hemolytic streptococci and 5(4.95%) patients had no growth after 48 h incuation. 40(39.6%) Patients had Gram positive bacteria while 71(70.3%) had Gram negative bacteria.

The mean of duration of PPROM was 9.7 with SD 16.8.

Conclusion: Various vaginal infections pose a risk of preterm premature rupture of membranes (PPROM) and negative effects for both the mother and the newborn. The predominant microbiological growth in the culture of the vaginal swab consisted of Gram-negative bacteria, Gram-positive bacteria, E. coli, Klebsiella pneumoniae, and Staphylococcus aureus.