Abstract

Background: This in vivo study aims to evaluate the clinical success of Platelet Rich Fibrin (PRF) in the revitalization and healing of periapical lesions related to necrotic young permanent incisors in a randomized controlled study.

Methods: This study was conducted on 31 teeth of 29 children in the age group of 8–11 years old who were selected with no sex predilection by predetermined inclusion criteria. All teeth were examined clinically to determine the clinical success over 6 months. Then all data were statistically analyzed using the Statistical Program for Social Sciences for Windows (SPSS), version 22 (IBM© Corporation, NY, USA). The Chi-square test was used to summarize the categorical data, including the frequencies of the participant's gender, tooth type, and baseline clinical criteria …

Result: The results demonstrated the clinical success of all cases after 12 months of treatment, with significant healing and the absence of the pre-apical sinus.

Conclusion:

Platelet-rich fibrin is an ideal scaffold that can be used with necrotic, immature teeth with pre-apical lesions.