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332303

Recurrence Risk in Thyroid Cancer Patients after Thyroidectomy

Article

Last updated: 28 Dec 2024

OverviewSimilar Items

Subjects

-

Tags

Preventive Medicine and epidemiology.

Abstract

Abstract:

Background: With rising thyroid cancer incidence in Egypt, understanding recurrence patterns and risk factors is crucial for optimizing survivorship care. This study examined disease-free survival (DFS) and prognostic factors for recurrence in Egyptian patients. Methods: Retrospective analysis of 99 pathologically confirmed thyroid cancer patients treated at the Minia Oncology Center between April 2022 and March 2023. DFS was estimated by Kaplan-Meier method. Multivariate Cox regression identified factors associated with recurrence. Results: Out of the 99 TC patients, 8 patients recurred (8.8%). Cumulative 1-, 5-, 10-year DFS was 98%, 94.6% and 83.5%. Regional metastasis at diagnosis (Hazard ratio [HR]=7.2, 95% CI 1.38-37.02, p=0.019) and diabetes (HR=26.2, 95% CI 1.03-33.6, p=0.047) were independent predictors of recurrence after adjusting for age and sex. Conclusions: Thyroid cancer patients treated at Minia Oncology center showed long-term DFS, with advanced stage at presentation and diabetes indicating greater recurrence risk. Understanding risk factors for recurrent disease could help personalize treatment and long-term follow-up in these patients.

DOI

10.21608/mjmr.2023.237786.1559

Keywords

Thyroid Cancer, Recurrence, Survival, Disease-Free Survival

Authors

First Name

Shaza

Last Name

Alkilany

MiddleName

Fadel

Affiliation

Department of Public Health , Faculty of Medicine, Minia University, Minia, Egypt

Email

shazafadel18@gmail.com

City

Minia

Orcid

0000-0002-0744-6166

First Name

Eman

Last Name

Mahfouz

MiddleName

Mohamed

Affiliation

Department of Public Health , Faculty of Medicine, Minia University, Minia, Egypt

Email

emanmahfouz39@yahoo.com

City

Minia

Orcid

-

First Name

Eman

Last Name

Mohammed

MiddleName

Sameh

Affiliation

Department of Public Health , Faculty of Medicine, Minia University, Minia, Egypt

Email

emansameh7@yahoo.com

City

Minia

Orcid

-

First Name

Eman

Last Name

Ghazawy

MiddleName

Ramadan

Affiliation

Department of Public Health, Faculty of Medicine, Minia University, Minia, Egypt

Email

emanghazawy@yahoo.com

City

Minia

Orcid

0000-0002-3807-6954

First Name

Yasser

Last Name

Abdelgwad

MiddleName

Mohammed

Affiliation

Department of Surgical Oncology, Minia Oncology Center, Minia, Egypt

Email

yasserabdelgwad5@gmail.com

City

-

Orcid

-

First Name

Nsreen

Last Name

Mohamadien

MiddleName

Ragab Ali

Affiliation

Department of Clinical Oncology and Nuclear Medicine, Faculty of Medicine. Assiut University, Assiut, Egypt

Email

nsreen284284@gmail.com

City

-

Orcid

0000-0002-5014-901X

First Name

Medhat

Last Name

Soliman

MiddleName

Mounir

Affiliation

Department of Surgical Oncology, Minia Oncology Center, Minia, Egypt

Email

medhatsoliman724@gmail.com

City

-

Orcid

-

First Name

Marwa

Last Name

Abdelrehim

MiddleName

Gamal

Affiliation

Department of Public Health, Faculty of Medicine, Minia University, Minia, Egypt

Email

marwagamal_84@yahoo.com

City

-

Orcid

-

Volume

35

Article Issue

1

Related Issue

46232

Issue Date

2024-01-01

Receive Date

2023-12-10

Publish Date

2024-01-01

Page Start

1

Page End

10

Online ISSN

2682-4558

Article File

MJMR_Volume 35_Issue 1_Pages 1-10.pdf

PDF . 390.7kB

Link

https://mjmr.journals.ekb.eg/article_332303.html

Detail API

https://mjmr.journals.ekb.eg/service?article_code=332303

Order

1

Type

Original Article

Type Code

2,212

Publication Type

Journal

Publication Title

Minia Journal of Medical Research

Publication Link

https://mjmr.journals.ekb.eg/

MainTitle

Recurrence Risk in Thyroid Cancer Patients after Thyroidectomy

Details

Type

Article

Created At

28 Dec 2024