Beta
302317

Optical coherence tomography angiography changes of the macula in early primary open angle glaucoma compared to healthy eyes

Article

Last updated: 28 Dec 2024

Subjects

-

Tags

Healthcare research

Abstract

Glaucoma is one of the distinguished causes of irreversible blindness. It affects about 3.54% of people over 40. Glaucoma is an optic neuropathy characterized by the progressive loss of retinal ganglion cells and their axons in the peripapillary retinal nerve fiber layer as well as distinctive changes in the optic nerve head (ONH). Visual field loss is a symptom of the damage as it progresses. Vascular insufficiency is one of the factors that may contribute to glaucoma. Given that the superficial retinal capillary plexus supplies RGCs, glaucoma could be associated with decreased superficial retinal microcirculation in the macular area. Purpose of the study: the current study aimed to evaluate the macular vessel density and GCC thickness changes in early POAG eyes and compare them with healthy eyes .patients and methods: The participants were divided into two groups according to visual field findings. Group1: included 20 eyes of 12 patients of early POAG. Group 2: included 20 eyes of 10 normal individuals. All participants underwent thorough ocular examination, OCT imaging of the ONH and OCT-A of the macula. Early POAG and healthy eyes data were compared. Results: GCC thickness and whole image vessel density (wiVD) in the superficial capillary plexus were lower in the early POAG group than in healthy eyes, whereas deep capillary plexus vessel densities did not differ significantly between both groups. conclusion the inclusion of OCTA in glaucoma diagnostics helps in the early detection of glaucoma and improves our understanding of ocular blood flow changes in the disease.

DOI

10.21608/mjmr.2023.209587.1393

Keywords

POAG, OCTA, Macular vessel density

Authors

First Name

Rabie

Last Name

Hassanen

MiddleName

Mohamed

Affiliation

Department of Ophthalmology, Faculty of Medicine, Minia University

Email

rabiehassanien@gmail.com

City

minia

Orcid

-

First Name

Ahmed

Last Name

Sabry

MiddleName

Mohamed

Affiliation

Department of Ophthalmology, Faculty of Medicine, Minia University

Email

ahmedsabry1965@yahoo.com

City

minia

Orcid

-

First Name

asmaa

Last Name

Mohamed

MiddleName

Anwar

Affiliation

Department of Ophthalmology, Faculty of Medicine, Minia University

Email

asmaa.anwar@mu.edu.eg

City

minia

Orcid

-

First Name

Jacklen

Last Name

Wahba

MiddleName

Gamal

Affiliation

ministry of health ophthalmology hospital

Email

jojagamal2017@gmail.com

City

-

Orcid

0009-0000-7331-4770

Volume

34

Article Issue

3

Related Issue

43488

Issue Date

2023-07-01

Receive Date

2023-05-10

Publish Date

2023-07-01

Page Start

81

Page End

89

Online ISSN

2682-4558

Link

https://mjmr.journals.ekb.eg/article_302317.html

Detail API

https://mjmr.journals.ekb.eg/service?article_code=302317

Order

10

Type

Original Article

Type Code

2,212

Publication Type

Journal

Publication Title

Minia Journal of Medical Research

Publication Link

https://mjmr.journals.ekb.eg/

MainTitle

Optical coherence tomography angiography changes of the macula in early primary open angle glaucoma compared to healthy eyes

Details

Type

Article

Created At

28 Dec 2024