Background: Hair greying is a natural age-related process. It is considered as a cosmetic, not a medical, condition. However, as the chances of developing a disease increase with age, many studies have postulated that hair greying could be a predictor of some aging diseases such as diabetes mellitus. Aim: The present study aims to reveal onset, pattern of hair greying and its correlation to diabetes mellitus among individuals with various age groups and of both sex in Minia governorate. Patients and methods: The present study was conducted on 5000 individuals answered a questionnaire Results:11.9% of premature hair greying cases were suffering from diabetes mellitus either type 1 or type 2 and were receiving a regular daily treatment (before and during onset of hair greying) either insulin for type 1 DM and/or oral hypoglycemic for type 2 DM Conclusion: premature hair greying can be considered an alarming factor for DM and others systemic diseases.