Abstract:
Objective: to detect vitamin D level in children with chronic suppurative otitis media (CSOM) in comparison to normal control group. Materials and Methods: Prospective comparative case control study was conducted on 85 children aged from 3 to 16 years at Otorhinolaryngology department, Minia University Hospital divided into 2 groups: Group A (case group) Forty-five cases with CSOM and Group B (control group) including Forty healthy children with normal Tympanic membrane (TM). Serum samples were used to assay the level of 25(OH) vitamin D. Vitamin D deficiency was considered as 25(OH)D <20 ng/ml. Results: Eighty-five children, divided into forty-five cases suffering from CSOM (15 males and 30 females) (Case group) and forty children (20 males and 20 females) with normal tympanic membrane (Control group). The mean vitamin D level in case group was 27.4 ± 22.1 while in control group was 35.6 ± 15.9. In case group Vitamin D deficiency was detected in 24 cases (53.3%), insufficient in 5 cases (11.1%), and sufficient in 16 cases (35.6%) while in control group, Vitamin D deficiency was detected in 5 cases only (12.5%), insufficient in 10 cases (25%), and sufficient in 25 cases (62.5%) with significant difference of vitamin D deficiency between case and control group. Conclusion: Vitamin D level in children with CSOM was found to be significantly lower than that in control group with normal TM, so assessment of vitamin D level is very important in children with CSOM to decrease recurrent acute exacerbation and prevent complications.