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279980

Correlations between MRI brain volumetric measurements and IQ scores in Egyptian children.

Article

Last updated: 28 Dec 2024

Subjects

-

Tags

Healthcare research

Abstract

Background: The correlation between IQ scores and brain structures is still unclear. The brain volume may be one of the neurophysiological indicators for assessment of intelligence in children. This study aims to find the correlation between IQ score levels in Egyptian children and the MRI volumetric measurements of brain structures in aberrantly normal conventional MRI. Methods: A retrospective study included fifty-one children with normal conventional brain MRI studies were referred from Children and Maternity Hospital, Minya University in the duration from October 2018 to December 2019. Their ages were ranged from 2 to 14 years. Inclusion criteria: child has delayed speech, hyperactivity or learning disabilities in preschool age with aberrantly normal conventional MRI examination, exclusion criteria: Children with an abnormal MRI brain examination or have a contraindication for MRI techniques were excluded from this study. All children presented with delayed speech or with history of delayed speech as early clinical sign of delayed milestone They suspected to convectional MRI and volumetric MRI examination & IQ test (Stanford-Binet intelligence scales: fifth edition). Volumetric MRI assessed by automated online processing using (VolBrian.com) pipeline. Result: 51 subjects were included in this study for an average age of 7.8±3.1year, the average IQ level was 64.69±13.9, with an average total brain volume 1227.96±204.26cm3. Despite positive correlation between IQ scores and brain radiographic measures, only total brain volume (p value = 0.024), intracranial cavity (p value = 0.041) and grey matter volume (p value = 0.009) had a statistically significant correlation with IQ levels. Additionally, males had a significant correlation between IQ scores and total brain volume (p value = 0.043) as well as grey matter volume (p value=0.012). Conclusion: Total brain volume is directly and significantly correlated with IQ scores in Egyptian children, especially in males. Further studies with more robust design are needed.

DOI

10.21608/mjmr.2023.181718.1245

Keywords

MRI, CNS, Egyptian children, Brain Volumetry, IQ

Authors

First Name

Mohamed

Last Name

Amin

MiddleName

Ahmed

Affiliation

Department of Diagnostic Radiology, Faculty of Medicine, Minia University, Minia, Egypt

Email

mohamed.ameen@mu.edu.eg

City

minia

Orcid

-

First Name

Samier

Last Name

Mounir

MiddleName

Mohamed

Affiliation

Department of Pediatrics, Faculty of Medicine, Minia University, Minia, Egypt

Email

sammmoner2@yahoo.com

City

Minia

Orcid

0000-0003-0821-7303

First Name

Nashwa

Last Name

Adel

MiddleName

Mohamed

Affiliation

Department of Diagnostic Radiology, Faculty of Medicine, Minia University, Minia, Egypt

Email

nashwaadelrad80@yahoo.com

City

-

Orcid

-

Volume

34

Article Issue

1

Related Issue

38684

Issue Date

2023-01-01

Receive Date

2022-12-18

Publish Date

2023-01-01

Page Start

76

Page End

85

Online ISSN

2682-4558

Link

https://mjmr.journals.ekb.eg/article_279980.html

Detail API

https://mjmr.journals.ekb.eg/service?article_code=279980

Order

11

Type

Original Article

Type Code

2,212

Publication Type

Journal

Publication Title

Minia Journal of Medical Research

Publication Link

https://mjmr.journals.ekb.eg/

MainTitle

Correlations between MRI brain volumetric measurements and IQ scores in Egyptian children.

Details

Type

Article

Created At

28 Dec 2024