Abstract:

Objective:

Coronavirus disease (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), became a pandemic in March 2020, affecting millions of people worldwide. However, COVID-19 in pediatric patients represents 1–5% of all cases, and the risk for developing severe disease and critical illness is much lower in children with COVID-19 than in adults.The clinical severity of the infection varies from a simple cold to severe acute respiratory syndrome (ARDS) or even death. Multisystem inflammatory syndrome in children (MIS-C), a possible complication of COVID-19, has been described as a hyperinflammatory condition with multiorgan involvement similar to that in Kawasaki disease or toxic shock syndrome in children with evidence of SARS-CoV-2 infection.

Methods: 148 children were selected for our study. The demographic data, clinical manifestation, and laboratory measurements were also collected from patient files .

Results: There was a statistically significant difference between positive covid-19 cases and negative cases as regarding inflammatory markers (CRP , LDH, D.Dimer and ferritin)

Keywords COVID-19 , Children. SARS-CoV-2 , inflammatory markers.