Abstract:

Background: Mechanical Ventilation is essential intervention, Every year, MV is administered to thousands of pediatric patients. The study aimed to assess the indications and outcomes of Mechanical Ventilation in all ventilated patients aged from 1 Month to 18 years in Minia University PICU. Methods: This is a Hospital based cross sectional study at Minia University Hospital PICU during the period Octobor 2019 to May 2022 in Minia governorate, Egypt. Results: About 54% were males 46% were females, the mean of age of all mechanically ventilated children was 25.6 ± 33.9 months. Non-Respiratory causes represents the majority of causes that leads to mechanical Ventilation in (54%) and the commonest non-respiratory causes was apnea after status epilepticus (11.6%) and central apnea (7.6%) causing respiratory failure in 48 (19.1%) infants.

Pneumonia was the commonest respiratory indication for mechanical ventilation in (33.5%). The mode that was used mostly was PCV in (86.1%) and the mean duration of mechanical ventilation was 4 ± 2.6 days. there is Significant correlation between mortality rate and indication for MV, duration of ventilation, relapse rate and complication rate (Spearman test, P < .05) and according to Binary logistic regression model, indication, duration, and complications of mechanical ventilation are the major determinants of the mortality outcome. Conclusions: VAP is more likely to be the most common complication of the Mechanical Ventilation. The outcome of mechanically ventilated patients depended on characteristics at the start of MV, as well as on the development of complications and management protocols in the PICU.