Organophosphate (OPh) pesticide remains the main agent for pest control. It is therefore likely to have adverse effects on farmers who are accidentally over exposed while handling these pesticides. It has also become an agent of choice for self- poisoning because of low cost and easy availability. OPh consumption accounts among the most cause of suicide in the world as 258,234 would die of organophosphate poisoning and they account for 30% of the suicidal cause worldwide. Accumulation of acetylcholine leads to cholinergic features; they can be broadly divided into central and peripheral symptoms. Vomiting, diarrhea, miosis muscle fasciculations, urinary incontinence and bronchoconstriction are the common muscarinic symptoms.