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309775

Gastric Endoscopic Mucosal Resection and Polypectomy among Patients with Liver Cirrhosis and Esophageal Varices in the setting of acute upper gastrointestinal bleeding

Article

Last updated: 05 Jan 2025

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Tags

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Abstract

Background
Gastric polyps are not infrequently reported among cirrhotic patients. Endoscopic resection of gastric polyps among patients with liver cirrhosis and esophageal varices carries the risk of post-polypectomy bleeding. This may explain why endoscopists are reluctant to its excision.
 
The aim is to evaluate the incidence of immediate (intraoperative) and delayed (within 30 days) post-polypectomy bleeding among cirrhotic patients with esophageal varices and portal ‎hypertension and determine its risk factors.
Methods‎
This study comprised 39 cirrhotic patients with portal hypertension and varices who presented with gastrointestinal bleeding, and they had gastric polyps detected during the endoscopic intervention to control the acute bleeding or during follow-up. All patients were exposed to the entire history, clinical examination, and basic laboratory workup. Esophagogastroduodenoscopy was done to combine bleeding control and polypectomy simultaneously.
Results
Immediate (intraoperative) post-polypectomy bleeding occurred in 38.8% of patients, and no delayed bleeding was reported. Most of the reported bleeding was mild and clinically non-significant, and it stopped spontaneously or endoscopically. Furthermore, no mortality was reported.
The risk of immediate (intraoperative) bleeding significantly increased with advanced age, advanced liver disease, increased portal hypertension with large varices, and decreased platelet count; meanwhile, the sex of patients, size, location, and method of polypectomy did not significantly increase the risk of gastric post-polypectomy bleeding among cirrhotic patients with portal hypertension and esophageal varices.
Conclusions.
Among patients with cirrhosis and portal hypertension, gastric polypectomy simultaneously done during endoscopic intervention for esophageal varices is considered a safe maneuver.

DOI

10.21608/ajgh.2023.209532.1032

Keywords

Gastric polypectomy, Liver cirrhosis, post polypectomy bleeding, Portal Hypertension

Authors

First Name

Bassam

Last Name

Salama

MiddleName

Mansour

Affiliation

Infectious and Endemic diseases department. Faculty of Medicine. Suez Canal University, Egypt

Email

bassammansour99@yahoo.com

City

egypt

Orcid

-

First Name

Amir

Last Name

Barakat

MiddleName

Abd-elhameed Ahmed

Affiliation

Internal medicine department, gastroenterology, and hepatology unit; Faculty of Medicine Zagazig University, Egypt.

Email

ameerbarakat2019@outlook.com

City

-

Orcid

-

First Name

Mahmoud

Last Name

sharafeddin

MiddleName

-

Affiliation

Internal medicine department, gastroenterology, and hepatology unit; Faculty of Medicine Zagazig University, Egypt.

Email

dr.mahmoudsharafeddin@gmail.com

City

-

Orcid

-

First Name

Ahmed

Last Name

Gad

MiddleName

-

Affiliation

Internal medicine department, gastroenterology, and hepatology unit; Faculty of Medicine Zagazig University, Egypt.

Email

ahmedgadmed@yahoo.com

City

-

Orcid

-

Volume

6

Article Issue

1

Related Issue

39391

Issue Date

2023-02-01

Receive Date

2023-05-05

Publish Date

2023-02-01

Page Start

60

Page End

82

Print ISSN

2735-5489

Online ISSN

2735-5497

Link

https://ajgh.journals.ekb.eg/article_309775.html

Detail API

https://ajgh.journals.ekb.eg/service?article_code=309775

Order

309,775

Type

Original Clinical

Type Code

2,189

Publication Type

Journal

Publication Title

African Journal of Gastroenterology and Hepatology

Publication Link

https://ajgh.journals.ekb.eg/

MainTitle

Gastric Endoscopic Mucosal Resection and Polypectomy among Patients with Liver Cirrhosis and Esophageal Varices in the setting of acute upper gastrointestinal bleeding

Details

Type

Article

Created At

28 Dec 2024