The aim of this study was to determine how manganese forms, inorganic or nano, at different levels, would affected the digestibility coefficients of nutrients and some blood biochemical parameters in broiler chicks. A total number of 180 one day - old broiler chicks (Arbor Acres plus) were used in factorial experiment (2x3) two supplementation forms (inorganic and nano) and three supplementation levels (0, 6 and 12 mg Mn/Kg diet). The 35-day experiment was carried out. Results of this study  showed that, birds fed diets incorporated with nano manganese recorded significantly higher  digestibility of (P≤0.01)  dry matter (DM), organic matter, (OM) crude protein (CP), nitrogen free extract (NFE) and total protein concentration (TP). No significantly effects were detected in albumin, globulin or glucose concentration values. Birds received diet incorporated with 12 mg Mn/kg diet recorded significantly increased in concentration (P≤0.01) of triglycerides and VLDL cholesterol. Birds fed basal diets enriched with 12 mg nano Mn/kg diet presented the lowest level (P≤0.01) of GPT value. In conclusion, the effect of Mn in nano form was positively more pronounced than the inorganic in broiler chicks.