The research deals with studying the effective effects of nanotechnology on improving and developing the design of interior spaces. It also addresses the technical challenges and recent developments in the field of nanotechnology, with a focus on how these developments affect interior design processes and improve the performance and aesthetics of interior spaces. The research works to highlight the benefits. The potential of nanotechnology to improve the quality and functionality of interior spaces, with a focus on sustainability and innovation in design, while reviewing the latest developments in this field related to the design of interior spaces such as applications of anti-bacterial and anti-viral nano-coatings, smart surfaces that interact with the surrounding environment, and smart fabrics with advanced properties. In addition, it addresses the effects of these developments on the design processes of interior spaces, including thermal and sound insulation, lighting, self-cleaning, safety, and comfort. The research also reviews future challenges and opportunities in this field, with directions for future research and industry applications to exploit the potential of technology. Nano in the design of interior spaces, the research provides a comprehensive assessment of the impact of nanotechnology on improving the aesthetics and functionality of interior spaces, which contributes to a deeper understanding of the applications of this advanced technology in the field of interior design.