Background: Respiratory failure requires mechanical ventilation to maintain gas exchange.Extubation means endotracheal tube removal, where ventilated children maintain an efficient gas exchange without ventilatory support. If extubation fails, the children will need reventilation. Therefore, after extubation, children must receive proper nursing care to prevent reventilation. Aim: This study aims to identify the relationship between nursing care provided for children post-extubated from mechanical ventilation and their reventilation. Settings: The study was conducted at the Pediatric Intensive Care Unit of Alexandria University Children's Hospital at El-Shatby. Subjects: A convenient sample of 50 extubatedchildren and all nurses provided care to these children. Tools: Three tools were used to collect the necessary data: Characteristics of Child and their Medical Data Assessment Sheet, Nursing Care Provided for Children Post-Extubated from Mechanical Ventilation Observational Checklist, and Reventilation Assessment Sheet. Results: Only 14% of the extubation children were reventilated. Apnea was the cause of reventilation in 57.1% of children, low oxygen saturation was the cause for 42.9 %, and 28.6% for bradycardia, while tachypnea and aspiration were the cause for 41.3% of reventilation. There was are the relationship between nursing care provided to children and their reventilation, where 93% of nurses had a satisfactory level of total care for not-reventilated children compared to 57.1% for reventilated ones.Conclusion: It was concluded that there is a relationship between the care provided to extubated children and their reventilation. Recommendations: Develop a bundle of care for extubated children to prevent their reventilation and encourage nurses to attend conferences and workshops to be updated in their knowledge.