Adsorption of uranium using activated charcoal has been investigated. To achieve this, experiments are conducted to determine the effects of various adsorption parameters, including initial uranium concentrations, contact time, pH, temperature, and active carbon particle size. The activated charcoal samples used, was obtained in this study from the National for Research Centre, Giza Governorate, Egypt. The samples of activated charcoal that were utilized. It were characterized by scanning microscopy and infrared spectra. The relationship between initial uranium concentration and adsorption was studied. The adsorption efficiency of uranium increases as the initial concentration does, reaching a maximum of 92.9% at 75 mg g-1. The optimal volume for the solution was 40 mL, the optimal contact time was 15 minutes, and the adsorption efficiency reached 81.3% at pH 5 and 35 °C. There was an increase in the uranium adsorption efficiency, which peaked at 81.75% at 0.4 g and 85% at 120 mesh. After that, we assessed activated charcoal's adsorption capacity and investigated uranium's adsorption equilibrium and kinetics.