Background: Increasing the productivity and meet unforeseen obstacles in organizations needs highly satisfied, innovative, and content professionals. Additionally, integrating spirituality into the workplace is a new way to enhance worker performance. Aim: The current study aimed to assess organizational facilitators of workforce agility and its relation to workplace spirituality among nursing school educators. Design: A descriptive correlative design was utilized to fulfill the study's aim. Setting: The study covered all Minia Governorate's nursing schools. Subjects:  Convenience sample including all nursing school educators who were on duty working at the study setting during the period of data collection (n=188). Tools: Facilitators of Workforce Agility scale and Workplace Spirituality scale. Results: Around three-quarters of nursing schools' educators have high level of agility facilitators, and two thirds had a high level of workplace spirituality. Also, a statistically high significant strong positive relation exists between workforce agility and workplace spirituality and the high levels of agility facilitators as well as workplace spirituality mainly favored to Minia nursing school educators. Conclusion: Workforce agility and workplace spirituality are positively impacted by empowerment and constructive organizational practices. Recommendations: Nursing schools would need to encourage instructors' spiritual behaviour and adaptability with both organisational procedures and empowerment.