Social functioning impairment is considered one of the essential characteristics of schizophrenic disorder which prevents patients from adhering to treatment and diminishes their satisfaction with life. This study aimed to evaluate the effect of psycho-educational program on social functioning among schizophrenic patients. Quasi-experimental research design was utilized in this study. A purposive sample of 50 schizophrenic patients at Minia Hospital for Mental Health and addiction treatment was included. Personal/clinical data sheet and the Social Functioning Scale were utilized. The study's results revealed that, at pre-test, (34%) of the study subjects exhibited low social functioning level, (56%) of them exhibited a moderate social functioning and only (10%) exhibited a high social functioning level. However, at post and follow up, there is a marked increase in the total social functioning score compared to the pre-test with highly statistically significant difference. Conclusion: Psycho-educational program was effective in enhancing schizophrenic patients' social functioning. Continuous provision of psycho-educational programs is recommended for schizophrenic patients to increase their social functioning.