Background: Nurses are the common link between different members of the health care team, and are subsequently responsible for the delivery and coordination of the majority of patient care. Equipping nurses with advanced knowledge and skills will therefore enable them to effectively contribute to the patient journey and to ensure quality care is provided. It is essential to know motivating factors and inhibiting factors of the nurses' participation in Postgraduate programs. Aim: to assess factors affecting registration on postgraduate program among bachelor nurses in selected central hospitals. Design: A descriptive research design was utilized in this study. Setting: The study was conducted at selected central hospitals including ( Maghagha ,Matay and Bani-Mazar).Subject: the study sample was included all nurses who have bachelor degree that working at selected central Hospitals during the period of data collection  (n=61) .Tools: one tool was used in this study to assess Motivating Factors and Inhibiting Factors among bachelor nurses questionnaire. Results: the majority of the sample (88.5%) have high level of motivating factors and half (50.8%) of the sample have moderate level of inhibiting factors. Conclusions: most of bachelor nurses had high level of motivating factors and half of them had moderate level of inhibiting factors. There was a negative correlation between motivating and inhibiting factors at the three selected hospitals. Recommendations:  The hospital administration should provide nurses with financial, moral support and reducing working hours for them to join the master's and doctoral programs for career development.