Beta
ManageSearchChatDiscover
396585

A pilot Study of Salivary Microbiome in Algerian Obese Adult Females: Insight into Obesity and Oral Health Relationship

Article

Last updated: 05 Jan 2025

OverviewSimilar Items

Subjects

-

Tags

Oral microbiology.

Abstract

Background: Obesity has become a significant global health care problem. Several studies have reported the important role of microbiome in the development of obesity. Nevertheless, the composition of salivary microbiome (SM) of obese people is still inconclusive. Objectives: this pilot study endeavored to profile the salivary microbiome of Algerian obese adult females and to investigate the relationship between obesity and oral health status. Methodology: Sixty adult females from two cities in Algeria (Tlemcen and Jijel) were included (obese N= 30, and normal weight N= 30). Unstimulated saliva was gathered for high-throughput sequencing of V3-V4 region of the 16S rRNA gene. Statistical analyses (Student's T-test and Chi-square test) were implemented in order to analyze the connection between obesity and oral health status, socio-economic status and lifestyle. Results: Overall, 15 phyla, 21 classes, 39 orders, 65 families and 147 genera were characterized in the saliva samples. Firmicutes, Bacteroidetes, Actinobacteria, Proteobacteria and Fusobacteria were the common phyla in the Algerian female population. Alpha diversity indices suggested increased species richness and decreased diversity among the obese group. Over-abundance of Pseudomonas has been reported in the obese group from Jijel City. The obese individuals revealed significantly lower physical activity, lower socioeconomic status and higher values of oral indices. Conclusion: This is the first investigation reporting the diversity of the salivary microbiome in obese and normal weight Algerian adult females and suggesting the direct association of socioeconomic status and oral health with obesity.   

DOI

10.21608/ejmm.2024.339285.1385

Keywords

Salivary microbiome, 16s rRNA gene, Obesity, oral health, Algerian females

Authors

First Name

Manel

Last Name

ZERAOULIA

MiddleName

-

Affiliation

Laboratory of Applied Microbiology in Food, Biomedical and Environment (LAMAABE), Department of Biology, Faculty of Nature and Life, Earth and Universe Sciences, Abou Bekr Belkaïd University of Tlemcen, Algeria

Email

manel.zeraoulia@gmail.com

City

-

Orcid

0009-0000-8991-2812

First Name

Houria

Last Name

OULED-HADDAR

MiddleName

-

Affiliation

Laboratory of Molecular Toxicology, Faculty of Nature and Life Sciences, University of Jijel, Algeria

Email

houledhaddar@yahoo.fr

City

-

Orcid

0000-0002-3880-7550

First Name

Hassen

Last Name

CHERAITIA

MiddleName

-

Affiliation

Department of Mathematics, Faculty of Exact Sciences and Informatics, University of Jijel, Algeria

Email

hassen.stat@hotmail.fr

City

-

Orcid

0000-0002-5604-7233

First Name

Kahina

Last Name

GRIBI

MiddleName

-

Affiliation

Laboratory of Applied Microbiology in Food, Biomedical and Environment (LAMAABE), Department of Biology, Faculty of Nature and Life, Earth and Universe Sciences, Abou Bekr Belkaïd University of Tlemcen, Algeria

Email

kahina.gribi@univ-tlemcen.dz

City

-

Orcid

0009-0004-4011-961X

First Name

Nihel

Last Name

KLOUCHE-KHELIL

MiddleName

-

Affiliation

4Laboratory of Applied Microbiology in Food, Biomedical and Environment (LAMAABE), Department of Biology, Faculty of Nature and Life, Earth and Universe Sciences, Abou Bekr Belkaïd University of Tlemcen, 13000 Tlemcen, Algeria; Laboratory of Experimental Surgery, Dental Surgery Department, Faculty of Medicine, Abou bekr Belkaïd University of Tlemcen, 13000 Tlemcen, Algeria

Email

nklouche2000@gmail.com

City

-

Orcid

0000-0002-8868-8211

Volume

34

Article Issue

2

Related Issue

51523

Issue Date

2025-04-01

Receive Date

2024-11-25

Publish Date

2025-04-01

Print ISSN

1110-2179

Online ISSN

2537-0979

Link

https://ejmm.journals.ekb.eg/article_396585.html

Detail API

https://ejmm.journals.ekb.eg/service?article_code=396585

Order

396,585

Type

New and original researches in the field of Microbiology.

Type Code

2,038

Publication Type

Journal

Publication Title

Egyptian Journal of Medical Microbiology

Publication Link

https://ejmm.journals.ekb.eg/

MainTitle

A pilot Study of Salivary Microbiome in Algerian Obese Adult Females: Insight into Obesity and Oral Health Relationship

Details

Type

Article

Created At

28 Dec 2024