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387068

Spotlights on rapid noninvasive diagnostic approaches for pediatric tuberculosis.

Article

Last updated: 28 Dec 2024

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Subjects

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Tags

Diagnostics

Abstract

Tuberculosis (TB) is one of upmost infectious agents with a great impact on the global health services worldwide. Annually, millions of children; referred as under fifteen years of age; had TB. Pediatric TB represents about twelve percent of TB global burden and seventeen percent of all deaths by tubercle bacilli infection. Furthermore, in 2024, WHO reported that at least 30% of children with new and previously treated TB had rifampicin (RIF) resistant; that accounted the double incidence reported in 2016. Infected children act as reservoirs of M. tuberculosis from whom, it can spread. Therefore, without successful detection and effective treatment, elimination strategies will be difficult to be achieved. It is important to highlight pediatric TB to know how far we are. In Egypt, researchers predict a static or increasing level especially with increased population growth and obvious risk factors e.g overcrowding and immunodeficiency. In 2023, WHO TB country profile estimated that the total TB incidence in Egypt was about ten per one hundred thousand population with six percent were children. Therefore, the unique vulnerabilities and different clinical presentations make the early and highly sensitive diagnostic procedures in this age, one of the most important challenges.

DOI

10.21608/ejmm.2024.327029.1355

Keywords

Pediatric tuberculosis, epidemic, Lipoarbinomman, Circulating Free DNA

Authors

First Name

Mervat

Last Name

Abdel-Aziz

MiddleName

A.T.

Affiliation

Department of Medical Microbiology and Immunology, Faculty of Medicine, Beni-Suef University, Beni-Suef, Egypt Department of Biomedical Sciences, Microbiology Division, College of Medicine, King Faisal University, Al-Ahsa, Saudi Arabia

Email

abdelazizmervat82@gmail.com

City

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Orcid

-

Volume

34

Article Issue

1

Related Issue

50252

Issue Date

2025-01-01

Receive Date

2024-10-09

Publish Date

2025-01-01

Print ISSN

1110-2179

Online ISSN

2537-0979

Link

https://ejmm.journals.ekb.eg/article_387068.html

Detail API

https://ejmm.journals.ekb.eg/service?article_code=387068

Order

387,068

Type

Review articles

Type Code

2,039

Publication Type

Journal

Publication Title

Egyptian Journal of Medical Microbiology

Publication Link

https://ejmm.journals.ekb.eg/

MainTitle

Spotlights on rapid noninvasive diagnostic approaches for pediatric tuberculosis.

Details

Type

Article

Created At

28 Dec 2024