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340262

Bacteriological Profile and Antimicrobial Resistance of Semen Infections among Infertility Cases before and during COVID-19 Pandemic: A Comparative Study

Article

Last updated: 28 Dec 2024

OverviewSimilar Items

Subjects

-

Tags

Antimicrobial agents

Abstract

Background; Antimicrobial resistance (AMR) among bacteria causing male genitourinary infections has the potential to affect male fertility. The objective of this work is to determine differences in AMR patterns of bacteria causing bacteriospermia in infertile men before and during the COVID-19 pandemic. Methods: This is an observational comparative study in which AMR of non-duplicate semen cultures from infertility cases before and during COVID-19 is presented. The COVID-19 cases are defined as per the protocol of the Ministry of Health and Population (MOHP) in Egypt. Antimicrobial susceptibility reporting was performed in agreement with the Clinical and Laboratory Standard Institute (CLSI, 2020). Results; A total of 176 samples were processed during the study period. 108 (61.4%) and 68 (38.6%) were of pre- and during the COVID-19 era. The commonest pathogens isolated were S. Aureus [60 (55.6%) and 40 (58.8%)], S. epidermidis [12 (11.1%) and 8 (11.8%)] and for N.gonorrhoea [11 (10.2%) and 6 (8.8%)] in pre-and during the COVID -19 period respectively. Significant antimicrobial resistance were observed for Nalidixic acid (P <0.001), Erythromycin (P <0.001) and Clarithromycin (P <0.001). Similar significant resistance were observed for Cefepime' (P <0.001) and Meropenem (P <0.001) antibiotics. Further, 22 (20.4%) isolates were multi-drug-resistant during the COVID-19 period. Conclusion; Pathogens presented significant levels of AMR in pre- and during the COVID-19 era. Further research with control groups is needed to better understand the effects of COVID-19 on male fertility.

DOI

10.21608/ejmm.2024.340262

Keywords

COVID-19, AMR, semen culture, Bacteriospermia, Male infertility

Authors

First Name

Naglaa

Last Name

Salem

MiddleName

E.

Affiliation

Department of Clinical Pathology, Faculty of Medicine, Suez Canal University, Egypt

Email

-

City

-

Orcid

-

First Name

Maha

Last Name

Anani

MiddleName

-

Affiliation

Department of Clinical Pathology, Faculty of Medicine, Suez Canal University, Egypt

Email

mahaenany77@gmail.com

City

-

Orcid

-

First Name

Fadia

Last Name

Mostafa

MiddleName

-

Affiliation

Department of Clinical Pathology, Faculty of Medicine, Suez Canal University, Egypt

Email

-

City

-

Orcid

-

First Name

Yasser

Last Name

Saleh

MiddleName

S.N.

Affiliation

Department of Dermatology, Suez Canal University, Egypt; College of Medicine at Shaqra, Shaqra University, Kingdom of Saudi Arabia

Email

-

City

-

Orcid

-

First Name

Shaimaa

Last Name

Amer

MiddleName

A.A.M.

Affiliation

Department of Public Health and Occupational Medicine, Faculty of Medicine, Suez Canal University, Egypt

Email

-

City

-

Orcid

-

First Name

Asmaa

Last Name

Hashem

MiddleName

A.

Affiliation

Department of Microbiology, Faculty of Medicine, Suez Canal University, Egypt

Email

-

City

-

Orcid

-

First Name

Altaf

Last Name

Bandy

MiddleName

-

Affiliation

College of Medicine at Shaqra, Shaqra University, Kingdom of Saudi Arabia

Email

-

City

-

Orcid

-

First Name

Amal

Last Name

Allithy

MiddleName

N.A.

Affiliation

Faculty of Medicine, Sohag University, Sohag, Egypt and Batterjee Medical College, Aseer, Saudi Arabia

Email

-

City

-

Orcid

-

First Name

Rania

Last Name

Saleh

MiddleName

M.

Affiliation

Department of Clinical Pathology, Faculty of Medicine, Suez Canal University, Egypt

Email

drrania82@yahoo.com

City

-

Orcid

-

Volume

33

Article Issue

2

Related Issue

45766

Issue Date

2024-04-01

Receive Date

2024-02-06

Publish Date

2024-04-01

Page Start

37

Page End

44

Print ISSN

1110-2179

Online ISSN

2537-0979

Article File

EJMM_Volume 33_Issue 2_Pages 37-44.pdf

PDF . 442.9kB

Link

https://ejmm.journals.ekb.eg/article_340262.html

Detail API

https://ejmm.journals.ekb.eg/service?article_code=340262

Order

340,262

Type

New and original researches in the field of Microbiology.

Type Code

2,038

Publication Type

Journal

Publication Title

Egyptian Journal of Medical Microbiology

Publication Link

https://ejmm.journals.ekb.eg/

MainTitle

Bacteriological Profile and Antimicrobial Resistance of Semen Infections among Infertility Cases before and during COVID-19 Pandemic: A Comparative Study

Details

Type

Article

Created At

28 Dec 2024