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326771

COVID-19 Vaccination Adverse Reactions among Vaccinated Persons in Mansoura University: A Prospective Study

Article

Last updated: 05 Jan 2025

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Subjects

-

Tags

virology

Abstract

Background: Health-care workers are at highest risk for COVID-19 and its complications. Vaccine development might be the best choice for ending this pandemic. Hence, studies are essential to follow the vaccination adverse reactions. Objectives: To determine the prevalence of adverse effects among COVID-19 vaccinated persons after getting the first and/or the second dosage of the vaccines. Methodology: This research was conducted on 509 vaccinated participants to investigate the adverse symptoms of the available COVID vaccines through an online survey. The questionnaire comprised 3 compartments; background, vaccination adverse symptoms and the comorbidities data. It was delivered to participants via social media. Results: Adverse symptoms were reported by more significant participants following the 1st dosage (n = 208, 80.0%) than following the 2nd dosage (n = 169, 67.9%) (P=0.002). The most prevalent adverse effects included fatigue, injection site pain, headache, fever, bone, and muscular pain. AstraZeneca and Sputnik led to more common adverse symptoms following 1st and 2nd doses. Females were more likely to experience post 1st dose (p=0.005) and 2nd dose (p=0.022) side effects. Resident doctors had higher odds (OR = 6.0 95% confidence interval [CI]:1.03 -35.1, p=0.029) than the other jobs to develop 1st dose post-vaccination effects. Participants with autoimmune and chronic diseases had a higher risk to develop post 1st dose adverse effects. Conclusion: About 80% of participants who obtained the COVID-19 vaccination experienced adverse effects. The most prevalent side effect following the 1st dosage was fatigue while pain at the injection site was the most prevalent symptom following the 2nd dosage.

DOI

10.21608/ejmm.2024.326771

Keywords

COVID-19 vaccine, adverse reactions, Healthcare workers, injection site pain, Online survey

Authors

First Name

Noha

Last Name

Mahmoud

MiddleName

M.

Affiliation

Medical Microbiology and Immunology Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt; Medical Microbiology & Immunology Department, Faculty of Medicine, Horus University, New Damietta, Egypt

Email

nohamostafa_81@yahoo.com

City

Mansoura

Orcid

https://orcid.org/00

First Name

Heba

Last Name

Eldegla

MiddleName

E.

Affiliation

Medical Microbiology and Immunology Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt

Email

heba_degla@yahoo.com

City

-

Orcid

-

First Name

Ragy

Last Name

Shenouda

MiddleName

N.

Affiliation

Medical Microbiology and Immunology Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt

Email

ragy_007@yahoo.com

City

-

Orcid

-

First Name

Amr

Last Name

Elsaeed

MiddleName

S.

Affiliation

General Surgery Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt

Email

amrsameer@yahoo.com

City

-

Orcid

-

First Name

Mohamed

Last Name

Mahmoud

MiddleName

M.

Affiliation

General Surgery Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt

Email

hamada_1985mmm@yahoo.com

City

-

Orcid

-

First Name

Doaa

Last Name

Alemam

MiddleName

-

Affiliation

Public Health and Community Medicine Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt; Public Health and Community Medicine Department, Faculty of Medicine, Horus University, New Damietta, Egypt

Email

dr_doaashokry@hotmail.com

City

-

Orcid

-

First Name

Nermin

Last Name

Abo El Kheir

MiddleName

Y.

Affiliation

Clinical Pathology Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt

Email

nerminyossef@yahoo.com

City

-

Orcid

-

First Name

Amira

Last Name

El-Ashry

MiddleName

H.

Affiliation

Medical Microbiology and Immunology Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt

Email

dr_amirah@mans.edu.eg

City

Mansoura

Orcid

-

Volume

33

Article Issue

1

Related Issue

44331

Issue Date

2024-01-01

Receive Date

2023-11-20

Publish Date

2024-01-01

Page Start

37

Page End

48

Print ISSN

1110-2179

Online ISSN

2537-0979

Article File

EJMM_Volume 33_Issue 1_Pages 37-48.pdf

PDF . 631.3kB

Link

https://ejmm.journals.ekb.eg/article_326771.html

Detail API

https://ejmm.journals.ekb.eg/service?article_code=326771

Order

326,771

Type

New and original researches in the field of Microbiology.

Type Code

2,038

Publication Type

Journal

Publication Title

Egyptian Journal of Medical Microbiology

Publication Link

https://ejmm.journals.ekb.eg/

MainTitle

COVID-19 Vaccination Adverse Reactions among Vaccinated Persons in Mansoura University: A Prospective Study

Details

Type

Article

Created At

28 Dec 2024