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319216

Pattern of Bacterial and Fungal Infections among Hospitalized Patients with COVID-19 versus non COVID-19 Community Acquired Pneumonia

Article

Last updated: 28 Dec 2024

OverviewSimilar Items

Subjects

-

Tags

Clinical microbiology

Abstract

Background: It is strongly believed that co-infections play an important role during COVID-19 outbreak. Furthermore, secondary bacterial pneumonia rates increase rapidly in intensive care unit patients. Objectives: This study aimed to elucidate the rate of bacterial and fungal contagions among the hospitalized COVID-19 patients and compares it with non-COVID-19 community acquired pneumonia (CAP) cases with documentation of the most common organisms to guarantee the responsible use of antibiotics among these cases. Methodology: 100 patients were admitted with confirmed CAP and classified into 2 groups according to SARS-CoV-2 PCR results; the first group consisted of 52 COVID-19 positive patients. The second group included 48 patients with non- COVID-19 CAP. Results: COVID-19 group showed several negative sputum cultures than the non-COVID-19 group (p=0.023). Within the cases with positive cultures, COVID-19 patients had more (Staph. aureus, E. coli, Klebsiella pneumoniae and Candida albicans). While non-COVID-19 patients had more (Streptococcus, Pseudomonas aeruginosa, Enterococcus and Proteus) (p <0.05). COVID-19 cases had further resistant strains (p =0.031). Regarding the outcome findings, there were considerable increase in duration of the hospital stay (LHS), necessity of oxygen support and mechanical ventilation among COVID-19 group [p <0.05] with a higher decease rate among COVID-19 group. Conclusions: Critically ill COVID-19 patients exhibited a higher rate of bacterial co-infection detected in sputum (80.8%), PSI, LHS, necessity for oxygen, mechanical ventilation and mortality were higher in COVID-19 CAP compared with non-COVID-19 CAP PSI, LHS, necessity for oxygen, mechanical ventilation and decease rate which were higher among COVID-19 cases compared with non-COVID-19 CAP.

DOI

10.21608/ejmm.2023.319216

Keywords

COVID-19, Coronavirus disease, SARS-CoV-2, CAP, bacterial coinfection

Authors

First Name

Basma

Last Name

Mohammed

MiddleName

-

Affiliation

Department of Medical Microbiology & Immunology, Faculty of Medicine, Aswan University, Aswan, Egypt

Email

basma.ali@med.aswu.edu.eg

City

-

Orcid

-

First Name

Ahmed

Last Name

Sadek

MiddleName

-

Affiliation

Department of Medical Microbiology & Immunology, Faculty of Medicine, Assiut University, Assiut, Egypt

Email

ahmedsadek1945@yahoo.com

City

Assiut

Orcid

-

First Name

Islam

Last Name

Sayed

MiddleName

G.

Affiliation

Department of Chest Diseases, Faculty of Medicine, Aswan University, Egypt

Email

islamgalal76@yahoo.com

City

-

Orcid

0000-0003-0844-4215

First Name

Mohamed

Last Name

Amin

MiddleName

M.

Affiliation

Department of Medical Microbiology & Immunology, Faculty of Medicine, Aswan University, Aswan, Egypt

Email

mohamed.mostafa@aswu.edu.eg

City

-

Orcid

-

Volume

32

Article Issue

4

Related Issue

42768

Issue Date

2023-10-01

Receive Date

2023-09-30

Publish Date

2023-10-01

Page Start

53

Page End

60

Print ISSN

1110-2179

Online ISSN

2537-0979

Article File

EJMM_Volume 32_Issue 4_Pages 53-60.pdf

PDF . 416.8kB

Link

https://ejmm.journals.ekb.eg/article_319216.html

Detail API

https://ejmm.journals.ekb.eg/service?article_code=319216

Order

319,216

Type

New and original researches in the field of Microbiology.

Type Code

2,038

Publication Type

Journal

Publication Title

Egyptian Journal of Medical Microbiology

Publication Link

https://ejmm.journals.ekb.eg/

MainTitle

Pattern of Bacterial and Fungal Infections among Hospitalized Patients with COVID-19 versus non COVID-19 Community Acquired Pneumonia

Details

Type

Article

Created At

28 Dec 2024