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307443

Molecular Detection of Human Norovirus among Children (0-5 Years) Attending Selected Hospitals in Kano Metropolis, Kano State, Nigeria

Article

Last updated: 05 Jan 2025

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Subjects

-

Tags

virology

Abstract

Background: Norovirus has been reported as the main cause of acute diarrhea worldwide after rotavirus. But its incidence in developing countries such as Nigeria has been underreported. Objectives: This study aimed to detect human Norovirus genogroups I, II and IV in stools of children (0-5 years) with diarrhea in three selected Hospitals (Muhammad Abdullahi Wase Specialist Hospital, Murtala Muhammad Specialist Hospital, and Hasiya Bayero Pediatric Hospital) in Kano, Nigeria, estimate the prevalence of Norovirus infection, determine the socio-demographic characteristics and other factors and examine the clinical profile of the study children in relation to their infection statuses. Methods: Two hundred (200) diarrheic fecal samples were collected from 0-5 years children between June-October 2021. The samples were examined for NoV using one-step real time reverse transcription-Polymerase chain reactions (RT-PCR) technique. Results: In this study, the total prevalence of Norovirus infection was found to be 21%, with Genogroups II having the highest frequency of 25 (12.5%), followed by Genogroup I having 11(5.5%), and Genogroup IV with the lowest 6(3.0%). Our investigation identified co-infections of three Norovirus genogroups: I and II (0.5%), I and IV (0.5%), and I, II and IV 2(1.0%). Conclusion: According to this study, Norovirus Genogroup II is the most common strain circulating in Kano, Nigeria, and it has been established that NoV is a relevant cause of pediatric diarrhea. However, there isn't any evidence linking the Norovirus to any other risk factors. In order to stop the spread of NoV, it is essential to keep the environment clean and further research is needed with more samples to find if possible link between risk factors and the presence of the virus.

DOI

10.21608/ejmm.2023.307443

Keywords

Norovirus, Genogroups, children, Kano metropolis, One-Step Real-time RT-PCR, diarrhea, acute gastroenteritis

Authors

First Name

Nusaiba

Last Name

Kabir Abubakar

MiddleName

K.

Affiliation

Department of Medical Microbiology and Parasitology, Faculty of Clinical Sciences, Bayero University, Kano Nigeria

Email

nusaibakabeeru@gmail.com

City

-

Orcid

-

First Name

Taysir

Last Name

Abdelrahman

MiddleName

R.

Affiliation

Department of Medical Microbiology and Parasitology, Faculty of Clinical Sciences, Bayero University, Kano Nigeria; Deoartment of Medical Microbiology and immunology, Faculty of Medicine, Al-Azhar University, Cairo Egypt

Email

dr.taysiralassuty@gmail.com

City

-

Orcid

-

First Name

Auwal

Last Name

Idris Kabuga

MiddleName

I.

Affiliation

Department of Medical Microbiology and Parasitology, Faculty of Clinical Sciences, Bayero University, Kano Nigeria

Email

aikabuga.mcp@buk.edu.ng

City

-

Orcid

-

First Name

Lawal

Last Name

Dahiru Rogo

MiddleName

D.

Affiliation

Department of Medical Microbiology and Parasitology, Faculty of Allied Sciences, Bayero University, Kano Nigeria

Email

ldrogo.med@buk.edu.ng

City

-

Orcid

-

Volume

32

Article Issue

3

Related Issue

41216

Issue Date

2023-07-01

Receive Date

2023-07-12

Publish Date

2023-07-01

Page Start

87

Page End

97

Print ISSN

1110-2179

Online ISSN

2537-0979

Article File

EJMM_Volume 32_Issue 3_Pages 87-97.pdf

PDF . 456.1kB

Link

https://ejmm.journals.ekb.eg/article_307443.html

Detail API

https://ejmm.journals.ekb.eg/service?article_code=307443

Order

307,443

Type

New and original researches in the field of Microbiology.

Type Code

2,038

Publication Type

Journal

Publication Title

Egyptian Journal of Medical Microbiology

Publication Link

https://ejmm.journals.ekb.eg/

MainTitle

Molecular Detection of Human Norovirus among Children (0-5 Years) Attending Selected Hospitals in Kano Metropolis, Kano State, Nigeria

Details

Type

Article

Created At

28 Dec 2024