The study aimed to know the nature and direction of the causal relationship between the money supply as main variable in monetary policy management and price stability indicators (inflation, and exchange rate ) in Sudan during period 2000-2022 and to emphasize the importance of diversifying monetary tools to control inflationary trends , their danger and their cost ,absolute dependence on the exchange rate tool .the problem of the study was the question is there a causal relationship linking the money supply , inflation , and the exchange rate in Sudan during the period 2000-2022? What is the direction of the relationship between the variable under study in Sudan during the study period ? the study used the descriptive analytical method and secondary sources were also used in this study , the quantitative approach is to build a standard model to measure the effect of the money supply and the exchange rate on inflation , by testing the causal relationship between the variables . from the results of the study there is a unidirectional causal relationship that goes from inflation to the exchange rate , that is the increase in inflation is the reason for the instability of the exchange rate in the term. Short term and that money supply has no effect on inflation in the long term.