Background: After a long history of axillary lymph node dissection surgeries, the current guidelines became
more supportive for the use of axillary sentinel node (SN) biopsy technique in a variety of situations. The use of
indocyanine green (ICG) fluorescence has recently gained momentum, because it is a viable and safe method for
the axillary sentinel node detection during breast cancer surgeries. In the presented case of this case report, the
indocyanine green dye was used as a tracer during a sentinel node biopsy, for the first time in Ain Shams University
Hospitals. The surgery was done for a thirty-eight-year-old female diagnosed with early breast cancer.
Conclusion: The indocyanine green fluorescence-guided axillary sentinel node biopsy in breast cancer is a feasible,
easy, and safe technique.