Background: Liposuction is mostly utilized to eliminate both deep and superficial fat deposits. Large volume
liposuction (LVL) plays a major role in reducing metabolic complications due to obesity. The study aimed to assess
the LVL effect in prediabetic patients regarding body weight, total body fat and changes during a 3- to 6-month
follow-up period.
Patients and method: This prospective clinical trial included 60 prediabetic patients with body mass index (BMI)
from 25 to 35 (Kg/m2) and varying degree of localized obesity.
Results: Weight, BMI and plasma insulin were significantly lower after 3 and 6 months after liposuction than
preoperatively and decreased after 6 months than after 3month postoperatively (P<0.001). LVL had positive
significant correlation with average of weight loss and BMI reduction (r= 0.0.948, r= 0.910 respectively, P< 0.0001).
Conclusion: LVL improved overweight by weight, BMI, and improve blood glucose level and plasma insulin level
over 3 m to 6 m follow up period.