Laparoscopic sleeve gastrectomy (LSG) comprises the first choice for treating morbid obesity in many
bariatric centers. In the era of modern laparoscopic techniques and minimally invasive surgery, tying and
knots have a limited role. New devices as ultrasonic and electrothermal bipolar have evolved in order to
achieve adequate haemostasis, tissue dissection and coagulation with reduced operating times. The aim of
this study was to compare the usage of Ligasure as one of the electrothermal bipolar devices and Harmonic
scalpel as one of the ultrasonic devices in devascularization of the greater curvature of the stomach during
LSG as regard the operative time and intra-operative and postoperative complications. There were no
statistically significant difference in the operative time and complications between both groups. The mean
operative time in Ligasure group was 100.50±15.95 minutes and in Harmonic group mean 97.71±8.21
minutes. Both Ligasure and Harmonic provide the surgeon comfort, time saving, safety and efficacy in such
a demanding operation. Choice between these two devices lies within the surgeon's preference.