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343966

Evaluation of Xylazine Ketamine Anesthesia in Rabbits Undergoing Tendon Surgery: A Prospective Randomized Controlled Study

Article

Last updated: 28 Dec 2024

OverviewSimilar Items

Subjects

-

Tags

Anesthesiology

Abstract

This study was designed to evaluate the effects of xylazine-ketamine anesthesia on reflexes and vital signs during and after tendon surgery in rabbits. Twenty healthy adult male rabbits (2-2.5 kg) were randomly assigned to two groups XK (Xylazine-ketamine) and K (ketamine). Intramuscular injections of xylazine (5 mg/kg) and ketamine (35 mg/kg), were given to rabbits. Clinical parameters (rectal temperature, heart rate, and respiratory rate) were estimated prior to injection (0 min) and at 5, 15, 30, 45, 60, 75, 90, and 120 minutes post-anesthetic injection, as well as reflexes (ear pinch reflex, and pedal reflex), were measured before and after anesthetic injection. In the XK group, we observed that rectal temperature increased considerably (P<0.05) at 5 and 15 minutes after induction and then gradually fell to preanesthetic control values. During the anesthetic phase, both groups' heart rates and respiration rates reduced significantly. In XK-injected rabbits, the return of reflexes was delayed. Surgical anesthesia lasted much longer in the animals of XK groups. The XK combination provided sufficient anesthesia for rabbits, as evidenced by a prolonged anesthetic period, and good cardiovascular and other clinical indices

DOI

10.21608/nvvj.2023.247402.1038

Keywords

Anesthesia, Ketamine, Rabbit, tendon, xylazine

Authors

First Name

Mahmoud

Last Name

Hassan

MiddleName

Atiya

Affiliation

Department of surgery, anesthesiology and radiology , Faculty of veterinary medicine, New Valley University

Email

mahmoud.atiya@vet.nvu.edu.eg

City

Egypt

Orcid

-

First Name

Mohamed

Last Name

Abd Elkawi

MiddleName

-

Affiliation

Department of surgery, Anesthesiology and Radiology, Faculty of Veterinary Medicine, New Valley University, 22751, El-Kharga, New Valley, Egypt.

Email

mohamedabdelkawi@vet.nvu.edu.eg

City

-

Orcid

-

First Name

Mahmoud

Last Name

Saber

MiddleName

S

Affiliation

Department of surgery, Anesthesiology and Radiology, Faculty of Veterinary Medicine, New Valley University, 22751, El-Kharga, New Valley, Egypt.

Email

salemzezo88@vet.nvu.edu.eg

City

-

Orcid

-

First Name

Waleed

Last Name

Senosy

MiddleName

-

Affiliation

Theriogenology Department, Faculty of Veterinary Medicine, New Valley University, Al Kharga, New Valley

Email

senosy_76@nvu.edu.eg

City

-

Orcid

0000-0002-8456-3382

First Name

Mahmoud

Last Name

Nassif

MiddleName

-

Affiliation

Department of surgery, Anesthesiology and Radiology, Faculty of Veterinary Medicine, Assiut University, Egypt.

Email

drmwt@hotmail.com

City

-

Orcid

-

First Name

Mohamed

Last Name

ElSherif

MiddleName

Wefky

Affiliation

Department of Surgery, Faculty of Veterinary Medicine, New Valley University, Egypt.

Email

mohamedelsherif@vet.nvu.edu.eg

City

-

Orcid

0000-0001-6483-6737

Volume

4

Article Issue

1

Related Issue

43334

Issue Date

2024-01-01

Receive Date

2023-11-08

Publish Date

2024-01-01

Print ISSN

2786-0272

Online ISSN

2786-0280

Article File

NVVJ3439661704060000.pdf

PDF . 1.6MB

Link

https://nvvj.journals.ekb.eg/article_343966.html

Detail API

https://nvvj.journals.ekb.eg/service?article_code=343966

Order

343,966

Type

Original Article

Type Code

1,934

Publication Type

Journal

Publication Title

New Valley Veterinary Journal

Publication Link

https://nvvj.journals.ekb.eg/

MainTitle

Evaluation of Xylazine Ketamine Anesthesia in Rabbits Undergoing Tendon Surgery: A Prospective Randomized Controlled Study

Details

Type

Article

Created At

28 Dec 2024