Background: Adolescence or early adult is considered a triggering developmental stage due to its threats affecting university students badly and leading them to a serious level of anxiety or a significant deterioration in their academic quality of life. Aim: This study aimed to investigate the relationship between anxiety and academic quality of life among university students. Design: A descriptive correlational design was obtained. Setting: The setting was selected from two different faculties (nursing & law) at British university in Egypt. Subjects: A purposive sample was selected with (234) university student that divided into (136 student from faculty of nursing, and 98 from faculty of law). The study tools were: (1st) A structured socio-demographic questionnaire, (2nd) Taylor manifest anxiety, and (3rd) Academic quality of life scale. Results: This study showed that there was a highly statistically significant negative correlation between anxiety and academic quality of life. Conclusions: Nursing students showed a higher level of anxiety more than law students, and in contrast, law students showed higher standard of academic quality of life. Recommendations: create a counseling hub in each faculty to help students who need academic support, design motivational programs to enhance positive reinforcement and encourage higher standards of academic quality of life, and arrange educational workshops involve students from various universities to develop students' ability acquiring more skills.