Background: Agricultural work considered as one of the most hazardous sectors in both developing and developed countries with high rates of accidental deaths, injuries, and work-related illnesses. The aim: Assessment of Health and Safety at work among Farmers Regarding Agriculture Hazards at Burqash Village in Giza Governorate. Research Design: Descriptive design used to conduct this study. Setting: the study will be conducted at Burqash Village- Imbaba- Giza Governorate, Sample: Convenient sampling technique used to choice (319) farmers. . Tool for data collection: One tool as interview questionnaire included five parts, 1st part: demographic characteristic, 2nd part: Past and present history of farmers, 3rd part: Farmers knowledge about agricultural hazards, 4th part: Farmers reported practice questionnaires and 5th part: Concerned with attitude regarding farmer health and safety. Results: 63% of the studied farmers exposed to agricultural injuries and hazards, 32.3 of farmers had average level of total knowledge. While, 62.4 of them had poor level of knowledge, while Shows 99.1% had unsatisfactory Levels of total reported practices while 0.9 % satisfactory Levels of total practices among farmers with mean 7.01±1.90 Conclusion: Shows significant relation between total score of knowledge and total score of reported practices among the studied sample while insignificant relation between total score of knowledge and total score of attitude and insignificant relation between total score reported practices and attitude , . Recommendation: providing educational programs to increase farmer's awareness about agricultural hazards, and replicate this research finding in another setting and large scale from farmers for generalization.