Beta
ManageSearchChatDiscover
314308

A Bayesian Approach for Estimating Twin Similarity with Respect to a Binary Trait Under the Beta-Binomial Model

Article

Last updated: 05 Jan 2025

OverviewSimilar Items

Subjects

-

Tags

-

Abstract

In twin studies there is a need to compare a sample of monozygotic to another independent sample of dizygotic twins with respect to the presence or absence of a specific disease or condition. A significant difference between the intracluster correlation coefficients between the two independent samples indicates the presence of a genetic component in the disease etiology, and is an estimate of twin similarity. In this paper, Bayesian statistical methodology is presented for the estimation of twin similarity with respect to a dichotomous trait. The parameter of interest is the difference between the intracluster correlation coefficients (ICC) of the two zygosity groups. Under the Beta- Binomial model, point and interval estimators for this difference, 4, are obtained.  

DOI

10.21608/esju.2011.314308

Keywords

beta, Binomial Model, Interval Estimation, Intracluster Correlation

Volume

55

Article Issue

1

Related Issue

43106

Issue Date

2011-06-01

Publish Date

2011-06-01

Page Start

10

Page End

21

Print ISSN

0542-1748

Online ISSN

2786-0086

Link

https://esju.journals.ekb.eg/article_314308.html

Detail API

https://esju.journals.ekb.eg/service?article_code=314308

Order

2

Type

Original Article

Type Code

1,914

Publication Type

Journal

Publication Title

The Egyptian Statistical Journal

Publication Link

https://esju.journals.ekb.eg/

MainTitle

A Bayesian Approach for Estimating Twin Similarity with Respect to a Binary Trait Under the Beta-Binomial Model

Details

Type

Article

Created At

28 Dec 2024