This study aimed to assess the impacts of pomegranate peel powder on growth performance, carcass characteristics and blood metabolites of Japanese quails. A total of 300 one-week-old male Japanese quails were randomly distributed into 4 equal groups (75 birds into 5 replicates/group). The 1st group (control) was fed the basal diet without any pomegranate peel powder, while pomegranate peel powder was added at levels of 300, 600, and 900 g per ton of feed, respectively in the 2nd, 3rd and 4th groups. At 5 wks of age, the best values of productive performance represented in body weight, weight gain, feed consumption and feed conversion ratio were achieved in groups fed diet supplemented with 900 g pomegranate peel powder/ton. No significant differences between all treatments for carcass characteristics were observed, except for the relative weights of lymphoid organs (bursa of Fabricius, thymus and spleen) which were improved by using pomegranate peel powder at the level of 900g/ton of feed. Additionally, dietary 900 g/ton pomegranate peel powder improved plasma concentration of total protein, albumin, globulin, triglycerides, cholesterol, HDL-cholesterol, and LDL-cholesterol. It could be concluded that, supplemented diet with pomegranate peel powder up to 900g/ton improved the productive performance traits, carcass characteristics and blood biochemical of Japanese quails.