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370617

EVALUATION OF NANO AND CONVENTIONAL FORMS OF LAMBDA-CYHALOTHRIN TOXICITY IN RATS

Article

Last updated: 28 Dec 2024

OverviewSimilar Items

Subjects

-

Tags

Forensic medicine and toxicology

Abstract

Nano-pesticides have been created to substitute traditional pesticides and enhance agricultural techniques. The utilization of nano-pesticides poses a considerable obstacle due to the insufficiency of information regarding their prospective ecotoxicity, especially animal, human, and other non-target organism toxicity. This study was conducted to evaluate the toxicity of the nano-emulsion Lambda-cyhalothrin compared with the conventional one, depending on investigating the organ weight index and histopathological examination of vital organs in treated rats. There was no significant difference between the effects of conventional and nanoform of Lambda cyhalothrin on body weight index. Still, there was a significant elevation in the relative weight of the liver and kidney in conventional Lambda cyhalothrin and nano-treated rats. Histopathological results of conventional Lambda cyhalothrin-treated rats indicated marked vacuolar degenerated hepatocytes, hypercellularity in the glomeruli, vascular hemorrhage in the cerebral cortex, and vacuolization of Leydig cells. While nano Lambda cyhalothrin-treated rats showed hepatocytes with dilated and congested blood vessels and Kupffer cell activation, necrosis of some renal tubular epithelium, and intratubular mononuclear cell infiltration. The cerebral cortex showed some pyknotic Purkinje cells, and spermatogenic cells were decreased.

DOI

10.21608/avmj.2024.294567.1275

Keywords

Nano pesticides, Pesticides, Lambda cyhalothrin, toxicity

Authors

First Name

ALIAA

Last Name

BAKHEET

MiddleName

A.

Affiliation

Animal Health Research Institute, Egypt.

Email

aliaa_ahmad47@yahoo.com

City

-

Orcid

0000-0002-6944-4887

First Name

EMAN

Last Name

ELSHARKAWY

MiddleName

E.

Affiliation

Department of Forensic Medicine and Toxicology, Faculty of Veterinary Medicine, Assiut University, Assiut, Egypt.

Email

medicine1971@yahoo.com

City

-

Orcid

-

First Name

GAMAL

Last Name

ZAYED

MiddleName

M.

Affiliation

Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Al-Azhar University, Assiut, Egypt.

Email

gamalzayed@hotmail.com

City

Assuit

Orcid

0000-0001-6777-3882

First Name

MAHMOUD

Last Name

EL-NASSER

MiddleName

A

Affiliation

Department of Forensic Medicine and Toxicology, Faculty of Veterinary Medicine, Assiut University, Assiut, Egypt.

Email

mmnasser2002@yahoo.com

City

Assuit

Orcid

-

First Name

DOHA

Last Name

AHMED

MiddleName

Y .

Affiliation

Department of Forensic Medicine and Toxicology, Faculty of Veterinary Medicine, Assiut University, Assiut, Egypt.

Email

dohayahia@yahoo.com

City

-

Orcid

-

First Name

SARY

Last Name

ABDEL-GHAFAR

MiddleName

KH.

Affiliation

Professor of Pathology and Clinical pathology Faculty of Veterinary Medicine, Assuit University

Email

sary64@windowslive.com

City

-

Orcid

-

First Name

MANAL

Last Name

SAYED

MiddleName

M.

Affiliation

Animal Health Research Institute, Egypt.

Email

monna192004@yahoo.com

City

Assuit

Orcid

-

Volume

70

Article Issue

183

Related Issue

49234

Issue Date

2024-10-01

Receive Date

2024-06-02

Publish Date

2024-10-01

Page Start

685

Page End

696

Print ISSN

1012-5973

Online ISSN

2314-5226

Article File

AVMJ_Volume 70_Issue 183_Pages 685-696.pdf

PDF . 1.8MB

Link

https://avmj.journals.ekb.eg/article_370617.html

Detail API

https://avmj.journals.ekb.eg/service?article_code=370617

Order

56

Type

Research article

Type Code

1,840

Publication Type

Journal

Publication Title

Assiut Veterinary Medical Journal

Publication Link

https://avmj.journals.ekb.eg/

MainTitle

EVALUATION OF NANO AND CONVENTIONAL FORMS OF LAMBDA-CYHALOTHRIN TOXICITY IN RATS

Details

Type

Article

Created At

28 Dec 2024