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361191

CORRELATION BETWEEN MACULAR AND IRIS AND MACULAR THICKNESS IN CONTROLLED VERSUS UNCONTROLLED DIABETIC PATIENTS

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Last updated: 28 Dec 2024

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Abstract

Background: Diabetes mellitus (DM) can lead to ocular complications, including diabetic
retinopathy (DR) and macular edema. The current research compared iris thickness (IT) and central
macular thickness (CMT) between controlled and uncontrolled diabetic patients. Methods: Sixty
patients participated in the cross-sectional study, aged ≥18 years with controlled (n=20) and
uncontrolled (n=20) DM, and non-diabetic controls (n=20). CMT and IT at1,2, and 3 millimeters
from the margin of the pupil were measured using optical coherence tomography (OCT) and
anterior segment imaging, respectively. Results: Compared to the control group, both diabetic
groups had considerably decreased CMT (p < 0.001), but comparable between controlled and
uncontrolled diabetics. There were no discernible variations in IT between the groups regardless
of the distance. The results showed that CMT and IT had a significantly negative correlation with
diabetics under control at 2 mm (r = -0.569, p = 0.008), but not at other distances. Conclusions:
Diabetic patients exhibited macular thinning regardless of glycemic control, while IT was
unaffected. Interestingly, lower CMT correlated with reduced IT at specific locations (IT2 and IT3)
in controlled diabetics, suggesting a potential relationship between these ocular parameters in
this population.

DOI

10.21608/ejco.2024.361191

Keywords

Diabetes mellitus, diabetic retinopathy, Macular Thickness, Iris thickness, Optical Coherence Tomography

Authors

First Name

Mohamed,

Last Name

M.

MiddleName

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Affiliation

Ophthalmology dept., Faculty of Medicine, Sohag, Univ., Egypt

Email

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Orcid

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First Name

Abdallah,

Last Name

A.

MiddleName

-

Affiliation

Ophthalmology dept., Faculty of Medicine, Sohag, Univ., Egypt

Email

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City

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Orcid

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First Name

Abdelsadek,

Last Name

A.

MiddleName

-

Affiliation

Ophthalmology dept., Faculty of Medicine, Sohag, Univ., Egypt

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Orcid

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Volume

7

Article Issue

1

Related Issue

48557

Issue Date

2024-06-01

Receive Date

2024-02-04

Publish Date

2024-06-01

Page Start

69

Page End

75

Print ISSN

2537-0502

Online ISSN

2537-0944

Article File

EJCO_Volume 7_Issue 1_Pages 69-75.pdf

PDF . 232.8kB

Link

https://ejco.journals.ekb.eg/article_361191.html

Detail API

https://ejco.journals.ekb.eg/service?article_code=361191

Order

9

Type

Original articles: include clinical trials, interventional research, Basic researches and clinically relevant laboratory investigations

Type Code

1,824

Publication Type

Journal

Publication Title

Egyptian Journal of Clinical Ophthalmology

Publication Link

https://ejco.journals.ekb.eg/

MainTitle

CORRELATION BETWEEN MACULAR AND IRIS AND MACULAR THICKNESS IN CONTROLLED VERSUS UNCONTROLLED DIABETIC PATIENTS

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Article

Created At

28 Dec 2024